1,3,5,7-四甲基-2,4,6,8-四乙基卟啉的合成  

Synthesis of tetraethyl - tetramethylporphyrin

作　　者：汪进[1] 魏月贞 张志谦 徐衍岭 

机构地区：[1]哈尔滨工业大学分析测试中心,黑龙江哈尔滨150001

出　　处：《哈尔滨工业大学学报》1999年第5期123-125,129,共4页Journal of Harbin Institute of Technology

摘　　要：四甲基-四乙基卟啉环系化合物有分布于整个分子体系的共轭π键，使其具有良好的光电性能，如较大的摩尔吸光系数，较长的磷光寿命和很高的光量子产率，在卟啉化学中的常被用作模型化合物．以乙酰乙酸乙酯和乙酰丙酮为起始原料，经Knorr反应合成吡咯环，并用二硼烷还原吡咯β位的羰基，为致活α位，该甲基用溴取代及胺基化反应制成胺基取代物，最后再经酸催化下的环合等五步反应合成了标题化合物，全程收率46％，该化合物的结构通过红外光谱，核磁共振谱和元素分析得到了验证．The distribution of conjugated π bond in the tetraethyl - tetramethylporphyrin (TETMP) molecule system make it possible ThMP has some good photoelectron properies such as a higher molar absorptive coefficient, longer phosphorescent lifetime and higher quantum yield. And TETMP is often used as a model compound in porphyrin chemistry. In the synthesis of TETMP, through Knorr reaction, reduction of the pyrrolic βacelyl, elecmphilic substitution of bromin and amin in the pyrrolic α - methyl and cyclization by acid catalysis, the tide compound was prepared by acetylaceticether and acetylacetone as the start materials. The smicture of the porphyrin was determined by FTIR, 1 HNMR and the elemental analysis.

关 键 词：四甲基 四乙基卟啉 合成 发光材料 红外光谱 

分 类 号：O626.13[理学—有机化学]