化痰养阴法对精液黏稠度的影响及机理研究  

Mechanism Research into the Effect of Dissolving Phlegm and Nourishing Yin Treatment on Human Semen Viscosity

作　　者：周文彬[1] 陈德宁[1] 洪志明[1] 黄忠旺[1] 黎杰运[1] 

机构地区：[1]广东省深圳市中医院男科,广东深圳518033

出　　处：《南京中医药大学学报》2011年第4期329-332,共4页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：广东省中医药局建设中医药强省科研资助项目(2010040);广东省深圳市科研计划项目(201003192)

摘　　要：目的观察化痰养阴法治疗精液黏稠度增高症(SHV)的临床疗效并探讨其作用靶点及机制。方法 88例SHV症患者随机分为治疗组(G1)和对照组(G2)。G1组依化痰养阴法服用中药辨证论治,G2组则口服维生素C+维生素E+锌硒宝片,4周为1疗程,共治疗3个疗程。采取计算机辅助精子分析技术(CASA)分析精液质量,并检测2组治疗前后精浆前列腺特异性抗原、前列腺3项(锌、酸性磷酸酶、柠檬酸)。结果治疗后2组精液黏稠度、精液质量、精浆前列腺特异性抗原、前列腺3项等各项指标均有所好转(P<0.05),但G1组较G2组为佳(P<0.05)。结论中医化痰养阴法治疗SHV有着良好的临床疗效,恢复紊乱的前列腺分泌功能有可能是其作用机制和靶点所在。OBJECTIVE To observe clinical therapeutic effects of dissolving phlegm and nourishing yin treatment on human semen hyperviscosity（SHV） and to explore its mechanism and acting targets.METHODS 88 SHV patients were randomly divided into treatment group（G1）,in which patients were given Chinese medicine of dissolving phlegm and nourishing yin based on syndrome differentiation,and control group（G2）,in which patients were administrated by vitamin C,E and Zinc-Selenium Tablets for 3 courses.4 weeks was 1 course.Besides,CASA was adopted to analyze semen＇s quality and detect prostate specific antigen in seminal plasma,three prostate indexes（zinc,acid phosphatase and citric acid） before and after treatment.RESULTS The indicators including hyperviscosity,quality and prostate specific antigen in seminal plasma of two groups after treatment improved（P0.05）,and G1 was superior to G2（P0.05）.CONCLUSION TCM treatment of dissolving phlegm and nourishing yin is of great clinical effects,whose mechanism and targets may lie in its regulation of the disordered secreting function of prostate gland.

关 键 词：化痰养阴法 精液黏稠度增高症 SHV 中医 

分 类 号：R256.56[医药卫生—中医内科学]