长效托宁救治有机磷农药中毒的临床分析  

Clinical analysis of penehyclidine hydrochloride on acute organophosphorus poisoning

作　　者：李土龙 

机构地区：[1]广东省湛江市南三卫生院内科,广东湛江524067

出　　处：《中国当代医药》2011年第19期63-64,共2页China Modern Medicine

摘　　要：目的:探讨长效托宁在救治有机磷农药中毒中的作用、疗效和安全性。方法:随机将65例口服有机磷农药中毒患者分为试验组45例和对照组20例。试验组应用氯磷定和长效托宁,对照组应用氯磷定和阿托品。结果:试验组45例中无死亡患者,对照组20例中死亡2例。在同等情况下长效托宁用药次数、用药总量明显小于阿托品(P<0.05),抢救成功率明显高于阿托品(P<0.05),副作用小。结论:长效托宁救治有机磷中毒优于阿托品,而且应用方便,毒副作用少,值得在基层医院推广。Objective：To explore the effect and security of penehyclidine hydrochloride on acute organophosphorus pesticide poisoning（AOPP）.Methods：65 patients who orally took the ganophosphorus were divided into the experimental group 45 cases and control group 20 cases stochastically.The experimental group used the pralidoxime chloride and pene hyclidine hydrochloride,control group used pralidoxime chloride and atropine.Results：The experimental group 45 examples had no death.The control group 20 examples,2 cases died.In the same level situation,the drugs using times and medication total quantity of penehyclidine hydrochloride were smaller than atropine obviously（P0.05）,the rescue success ratio was higher than atropine obviously（P0.05）.The side effect was small.Conclusion：The effect of penehyclidine hydrochloride on acute organophosphorus pesticide poisoning is better than atropine,it has convenient applying,little side ef fects.It is worth promoting in the basic unit hospital.

关 键 词：有机磷中毒 长效托宁 阿托品 优点 副作用 

分 类 号：R595.4[医药卫生—内科学]