1.5T MRI对Chiari Ⅰ型畸形颈髓角的测量与分析  

Measurement and analysis of cervico-medullary angle of patients with Chiari type 1 malformation on 1.5T MR imaging

作　　者：吕宝华[1,2] 程晓娟[2] 宋大伟[2] 张忻宇[1] 

机构地区：[1]青岛大学医学院,山东青岛266021 [2]泰山医学院附属泰山医院,山东泰安271000

出　　处：《泰山医学院学报》2011年第4期267-269,共3页Journal of Taishan Medical College

摘　　要：目的在MRI片上测量国人及Chiari Ⅰ型畸形的颈髓角,并对比分析,探讨其临床意义,为诊断Chiari Ⅰ型畸形提供一个可靠的参考标准。方法选择126例国人成人（18~74岁）正常头颅的MRI片,测量其上颈髓与延髓中心轴线两直线间的夹角,即颈髓角。结果 126例颈髓角最小值156°,最大173.9°,平均166.2°,95%可信区间为159.77°~171.14°;20例Chiari Ⅰ型畸形患者,最大角度为173.2°,最小角度为159.9°,其样本均数95%可信区间为160.25°~172.02°。正常组与病例组该角度大小差异有显著性（P=0.000）。结论对于Chiari Ⅰ型畸形的诊断,MR能够直接显示脑桥延髓受压及小脑下疝的情况,在MRI成像中可以参考以上参考值对于该疾病作出正确的诊断。Objective： To determine the angle between medulla oblongata and upper spinal cord on midsagittal MRI in normal Chinese individuals and patients with Chiari type 1 malformation to provide a clinical reference and study their clinical significance by MRI.Methods： 126 Chinese with no evidence of CNS abnormity and 20 patients with Chiari type 1 malformation diagnosed by X-ray film were studied by MRI.The measurement was performed on the central sagittal slice.Results： The normal cervico-medullary angle had a minimum of 156°,maximum of 173.9° and mean angle of 166.2° with the 95% confidence interval of 159.77°～171.14°.The estimating range of the angle of the Chiari type 1 malformation patients group had a minimum of 159.9°and maximum of 173.2° with the 95% confidence interval of 160.25°～172.02°.Normal group and the size of the angle difference between the case group were significant in the referential range of the normal natural angle between medulla oblongata and upper spinal cord（P=0.000）.Conclusion： For the diagnosis of Chiari type 1 malformation,MR can directly display the medulla oblongata pons and cerebellum herniation pressure situation,which has reference value for the above to make the correct diagnosis of the disease in MRI imaging.

关 键 词：磁共振成像 颈髓角 测量 CHIARI Ⅰ型畸形 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742.89[医药卫生—诊断学]