原发性高脂血症中医证候规律研究  

Probe on the rule of syndromes of TCM of primary hyperlipidemia

作　　者：唐大晅[1] 曹征[1] 金章安[1] 郭维琴[2] 

机构地区：[1]北京中医药大学东方医院心内科,100078 [2]北京中医药大学东直门医院心内科

出　　处：《环球中医药》2011年第4期270-272,277,共4页Global Traditional Chinese Medicine

摘　　要：目的应用因子分析与典则相关分析的方法研究原发性高脂血症的中医证候分类及其规律,为原发性高脂血症证候分类及临床治疗提供科学依据。方法以符合临床流行病学要求的多家医院280例临床资料为依据,采用因子分析的方法对采集的中医四诊信息进行统计学处理,得出的中医证候分类,再以典则相关分析研究其规律。结果原发性高脂血症的中医证型可分为9个类别:类阴虚火旺证12例,占4·29%;类脾气虚证39例,占13·93%;类肝郁气滞兼有郁热证20例,占7·14%;类血瘀证20例,占7·14%;类肾虚、痰瘀互结证26例,占9·29%;类肾气亏虚证52例,占18·57%;类心气虚证54例,占19·29%;类阳虚证13例,占4·64%;类痰浊阻遏证44例,占15·71%。原发性高脂血症患者的年龄与类肾虚、痰瘀互结证,体重指数与类痰浊阻遏证均呈正相关。结论本研究通过对原发性高脂血症中医证候规律的研究,获得临床证候分布及其规律,对中医药研究原发性高脂血症具有一定的意义。Objective To employ factor analysis and canonical correlation analysis in classification and discipline of primary hyperlipidemia syndromes in TCM,and to provide evidence for syndrome differentiation and clinical treatment.Method The research based on 280 clinical cases from multiple hospitals qualified with clinical epidemiology criteria.Factor analysis was employed in statistic process for TCM information of four examinations to summarize the syndromes classification.Canonical correlation analysis was used to quest the discipline.Result TCM syndromes for primary hyperlipidemia could be classified into 9 types：12 Cases of analogical syndrome of yin deficiency with effulgent fire（4.29%）.39 cases of analogical syndrome of spleen qi deficiency（13.93%）.20 cases of analogical syndrome of liver depression and qi stagnation with heat depression（7.14%）.20 cases of analogical syndrome of blood stasis（7.14%）.13 cases of analogical syndrome of kidney deficiency and binding of phlegm and stasis（9.29%）.52 cases of analogical syndrome of kidney qi deficiency（18.57%）.54 cases of analogical heart qi deficiency syndrome（19.29%）.13 cases of analogical yang deficiency syndrome（4.64%）.44 cases of analogical syndrome of phlegm turbidity obstruction（15·71%）.Age of patients with primary hyperlipidemia was positively correlated with analogical syndrome of kidney deficiency and binding of phlegm and stasis.Body mass index was also positively correlated with analogical syndrome of phlegm turbidity obstruction.Conclusion Classification and discipline of clinical syndromes are summarized by this study on TCM pattern types of primary hyperlipidemia,which has certain significance for primary hyperlipidemia TCM research.

关 键 词：原发性高脂血症 中医证型 因子分析 典则相关分析 

分 类 号：R259[医药卫生—中西医结合]