荨麻疹外周血T淋巴细胞及亚群的检测  

Determination of peripheral blood T lymphocytes and their subsets in patients with urticaria

作　　者：唐亚娟[1] 

机构地区：[1]常州市第一人民医院皮肤科,213003

出　　处：《临床皮肤科杂志》1999年第5期284-285,共2页Journal of Clinical Dermatology

摘　　要：对60例荨麻疹患者用流式细胞仪检测外周血T淋巴细胞及其亚群并与20例健康志愿者作对照。结果表明 ,荨麻疹患者CD3+及CD4 +细胞明显降低 ,与健康对照组比较差异有非常显著性意义(P<0.01),其中以急性荨麻疹患者CD3+、CD4+改变最为明显。实验结果表明 ,荨麻疹患者存在着T淋巴细胞免疫功能紊乱现象 ,在荨麻疹的发病中 ,不但有体液免疫参与 ,而且细胞免疫在荨麻疹的发病中亦有一定的作用。The peripheral blood T lymphocytes and their subsets in 60 patients with urticaria were detected by flow cytometry and compared with 20 healthy controls. The results showed that the number of CD3+and CD4+cells in the urticaria group was significantly lower than that of control group (P< 0.01), especially in patients with acute urticaria. The results showed that there was immunologic dysfunction of T lymphocyte in the patients with urticaria. It is the author's opinion that not only humoral immunity takes part but also cellular immunity plays a definite role in the pathogenesis of urticaria.

关 键 词：荨麻疹 T细胞亚群 流式细胞仪 T细胞 

分 类 号：R758.240.4[医药卫生—皮肤病学与性病学]