左旋布比卡因与布比卡因蛛网膜下腔麻醉在老年前列腺手术中麻醉效果的比较  

Comparison of levobupivacaine and bupivacaine in spinal anesthesia during transurethral resection of prostate for elderly patients

作　　者：李建[1] 金国光[1] 叶卫东[1] 

机构地区：[1]民航总医院麻醉科,北京100123

出　　处：《中华全科医师杂志》2011年第7期501-503,共3页Chinese Journal of General Practitioners

摘　　要：将择期行前列腺电切术的80例老年患者，随机均分为观察组与对照组（各40例），分别采用0．5％左旋布比卡因与0．5％布比卡因行蛛网膜下腔麻醉（腰麻）。观察组患者腰麻的感觉神经阻滞级别、维持时间分别为第（7±4）胸神经和（224±28）min，与对照组的第（6±3）胸神经和（227±30）min相似（均P〉0．05）。注药后5—30min，对照组平均动脉压为（71±8）～（72±8）mmHg（1mmHg=0．133kPa），低于观察组的（75±9）mmHg（P〈0．05）。两组低血压和恶心的发生率明显不同，低血压分别为10％（4／40）与30％（12／40），恶心分别为0％（0／40）与15％（6／40）（均P〈0．05）。采用0．5％左旋布比卡因腰麻用于行前列腺电切术的老年患者与0．5％布比卡因腰麻有相似的麻醉效果，但对血流动力学的影响及不良反应少，更适合用老年患者。Eighty elderly patients undergoing elective resection for the prostate were randomly divided into two groups, the levobupivacaine （observe group） and bupivaeaine （control group） were used for spinal anesthesia, respectively. The level of sensory block and maintain time were T7±4 and （224±28 ） rain in observed group, those in control group were T6±3 and （ 227±30 ） rain, respectively （ both P 〉 0. 05 ）. The mean arterial blood pressure of control group was （71±8 ） - （72 ±8 ） mm Hg （1 mm Hg = 0. 133 kPa） from 5 to 30 min after injection; meanwhile that of observed group was（75±9）ram Hg （P 〈 0. 05）. The incidences of hypotension and nausea were 10% （4/40）and 0% （0/40）respectively in observe group, and those were 30% （12/40） and 15% （ 6/40 ） respectively in control group （ both P 〈 0.05 ）. The results indicate that levobupivacaine and bupivaeaine have similar anesthetic effects, but levobupivacaine has fewer side effects and is more suitable for elderly patients.

关 键 词：麻醉 左旋布比卡因 

分 类 号：R614[医药卫生—麻醉学]