鼻病毒感染与哮喘急性加重的细胞学机制研究进展  

Progress in cellular mechanisms of rhinovirus infection and asthma acute exacerbation

作　　者：侯渊涛(综述)[1] 尚云晓(审校)[1] 

机构地区：[1]中国医科大学附属盛京医院儿科,沈阳110004

出　　处：《国际儿科学杂志》2011年第4期367-369,共3页International Journal of Pediatrics

摘　　要：支气管哮喘（哮喘）是一种由多种细胞和细胞组分导致的慢性气道炎症疾患，其发病机制复杂。有关病毒感染与哮喘急性加重的关系早已引起学者们的关注，尤其是鼻病毒。鼻病毒感染所致哮喘急性加重的机制涉及多种细胞、细胞因子和趋化因子。其中，嗜酸性粒细胞、T细胞、树突细胞、巨噬细胞和中性粒细胞等炎症细胞起了重要作用。研究这些机制对于哮喘的有效预防和治疗有重要意义。Bronchial asthma is a chronic inflammatory disorder of the airways caused by many cells and cellular elements. The mechanisms of asthma are complex. The relationship between virus infection and asthma acute exacerbation has attracted scholars＇ attention, especially rhinovirus. The mechanisms of asthma acute exacerbation caused by rhinovirus infection involve many cells, cytokines and chemokines. Among them, eosinophils, T lymphocytes, dendritic ceils, macrophages and neutrophils play important roles. These mechanisms are imoortant for effective orevention and treatment of asthma.

关 键 词：支气管哮喘 鼻病毒 炎症细胞 

分 类 号：R562.25[医药卫生—呼吸系统]