硫酸腺嘌呤预处理大鼠后心肌细胞糖原的定量分析  

A Quantitative Analysis of the Changes of Polysaccharides in Myocardium of the Rat with Ischemic Preconditioning by Sulphuric-Acid-Adenine

作　　者：雷岳山 袁玉林 汪艳 张友云 冯晓祥 

机构地区：[1]武汉基础医学院人体解剖学教研室,武汉430071 [2]武汉基础医学院实验中心,武汉430071

出　　处：《湖北医科大学学报》1999年第4期270-271,共2页

基　　金：湖北省自然科学基金!95J31

摘　　要：通过组化定量分析的方法，观察外源性硫酸腺嘌呤预处理及缺血再灌注的糖原稳定性的变化，探讨硫酸腺嘌呤对心肌缺血再灌注损伤的保护作用。结果显示；硫酸腺嘌呤预处理组平均光密度值与正常组差异无显著性，提示硫酸腺嘌呤显示明显的预处理效应。By IBAS image analysis system, the changes of polysaccharides in rat heart caused by traditional way and byextrinsic sulphuric-acid-adenine were quantitatively analysed in comparison wlth those in normal ischemia/reper-fusion. We aimed at observing the protective effect of extrinsic sulphuric-acid-adenine on ischemia/reperfusion in-jury to rat heart. The results showed that compared to the normal group, OPTDMs of the traditional way groupand the extrinsic sulphuric-acid-adenine group had no significant difference, and OPTDM of the ischemia/reper-fusion group reduced significantly. Therefore, the results manifested the effect of extrinsic sulphuric-acid-adenineof anti-i1ljury in myocardium caused by ischemic reperfusion.

关 键 词：硫酸腺嘌呤 心肌缺血 糖原 再灌注损伤 预处理 

分 类 号：R542.2[医药卫生—心血管疾病] R364.2[医药卫生—内科学]