Cerebrospinal fluid flow in empty sella syndrome and normal sellar regions measured by phase-contrast quantitative magnetic resonance  

作　　者：Weidong HU Li Xiang Xiurong Wang 

机构地区：[1]Department of Radiology, Central Hospital of Longgang District, Shenzhen 518116, Guangdong Province, China [2]Deparment of Intemal Medicine, Central Hospital of Longgang District, Shenzhen 518116, Guangdong Province, China

出　　处：《Neural Regeneration Research》2011年第11期816-820,共5页中国神经再生研究（英文版）

基　　金：Science and Technology Project of Longgang District in Shenzhen, No. YW2007044, YLL2010064

摘　　要：We used MRI to examine 38 healthy females and 38 female patients with empty sella syndrome. Cerebrospinal fluid flow was examined in six regions of interest, including the anterior clinoid processes, posterior clinoid processes, and 1.0 mm, 1.0 mm, 2.0 mm, --2.0 mm from the midpoint of the line between the anterior and posterior clinoid processes. The results revealed no significant differences in cerebrospinal fluid flow velocity and discharge in a single cardiac cycle, or indicators of cardiac cycles in the control group, indicating that the cerebrospinal fluid flow was relatively steady in the saddle area of the normal brain. In the empty sella syndrome group, cerebrospinal fluid hernia into the saddle area triggered a fluctuation of the anterior and posterior clinoid processes in the saddle area, while the flow in other regions in the saddle area was relatively steady this resulted in significant differences in cerebrospinal fluid flow velocity and discharge, as well as the cardiac cycle.We used MRI to examine 38 healthy females and 38 female patients with empty sella syndrome. Cerebrospinal fluid flow was examined in six regions of interest, including the anterior clinoid processes, posterior clinoid processes, and 1.0 mm, 1.0 mm, 2.0 mm, --2.0 mm from the midpoint of the line between the anterior and posterior clinoid processes. The results revealed no significant differences in cerebrospinal fluid flow velocity and discharge in a single cardiac cycle, or indicators of cardiac cycles in the control group, indicating that the cerebrospinal fluid flow was relatively steady in the saddle area of the normal brain. In the empty sella syndrome group, cerebrospinal fluid hernia into the saddle area triggered a fluctuation of the anterior and posterior clinoid processes in the saddle area, while the flow in other regions in the saddle area was relatively steady this resulted in significant differences in cerebrospinal fluid flow velocity and discharge, as well as the cardiac cycle.

关 键 词：cerebrospinal fluid magnetic resonance imaging empty sella syndrome cardiac cycle neuroimaging 

分 类 号：Q592.5[生物学—生物化学] O482.531[理学—固体物理]