Optimal stimulation parameters for Renzhong (DU 26) electro-acupuncture for improving motor function in a rat model of middle cerebral artery occlusion  

作　　者：Lin Han Shu Wang Jinquan Ma Wenping Yao Yan Shen Xuemin Shi 

机构地区：[1]Acupuncture Institute of First Affiliated Hospital, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China [2]Key Laboratory of Cerebropathy Acupuncture Therapy of State Administration of Traditional Chinese Medicine, Tianjin Key Laboratory of Acupuncture and Moxibustion, Tianjin 300193, China

出　　处：《Neural Regeneration Research》2011年第12期929-934,共6页中国神经再生研究（英文版）

基　　金：the National Natural Science Foundation of China,No.30873304

摘　　要：The selection of electro-acupuncture parameters remains poorly unified between clinical studies. The present study observed the effects of electro-acupuncturing Renzhong （DU 26） with different stimulation parameters on motor function recovery following middle artery occlusion injury in rats. Results showed an optimal stimulation parameter for Renzhong electro-acupuncture that was low frequency and mild current （2 Hz, 1 mA） significantly improved cortical excitability and conductive function, and promoted recovery in a rat model of motor function in middle artery occlusion. Frequency had a greater impact than current or interaction, and played a critical role in electro-acupuncture therapy.The selection of electro-acupuncture parameters remains poorly unified between clinical studies. The present study observed the effects of electro-acupuncturing Renzhong （DU 26） with different stimulation parameters on motor function recovery following middle artery occlusion injury in rats. Results showed an optimal stimulation parameter for Renzhong electro-acupuncture that was low frequency and mild current （2 Hz, 1 mA） significantly improved cortical excitability and conductive function, and promoted recovery in a rat model of motor function in middle artery occlusion. Frequency had a greater impact than current or interaction, and played a critical role in electro-acupuncture therapy.

关 键 词：ELECTRO-ACUPUNCTURE ACUPOINT middle artery occlusion injury motor-evoked potential stimulation parameters orthogonal design 

分 类 号：S853.61[农业科学—临床兽医学] S858.966[农业科学—兽医学]