氟化物在正畸釉质黏结剂中的应用  

Application of fluorid in orthodontic enamel adhesive

作　　者：张晓慧[1,2] 刘梅天[1] 冯致远[3] 冉海群[3] 刘斌[3] 

机构地区：[1]西北民族大学口腔国家民委重点实验室,甘肃省兰州市730030 [2]解放军第一医院,甘肃省兰州市730030 [3]兰州大学口腔医学院,甘肃省兰州市730000

出　　处：《中国组织工程研究与临床康复》2011年第21期3925-3928,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：甘肃省科技支撑项目(0708NKCA103)~~

摘　　要：背景:釉质脱矿是固定矫治技术中常见的并发症,氟化物的应用可以抑制釉质脱矿的发生并促进釉质再矿化。目的:了解氟化物预防釉质脱矿的可能机制和在釉质黏接剂中的应用,降低正畸过程中釉质脱矿后白斑的发生。方法:以"fluoride release,enamel demineralization,enamel adhesive,orthdontics treatment"为检索词,检索PubMed数据库(1990-01/2010-08);以"正畸治疗;牙釉质脱矿;氟化物"为检索词,检索中国期刊全文数据库(1990-01/2010-08)。文献检索语种限制为英文和中文。纳入与释氟黏接材料研制及临床应用研究相关内容。结果与结论:氟通过置换羟磷灰石晶胞部分羟基,使磷灰石的结晶性、稳定性和硬度得到增强。氟离子可以和唾液中的钙、磷离子共同组成矿化系统发挥促进脱矿釉质再矿化的作用。研制含有缓释氟源的树脂黏接剂是预防釉质脱矿的一个重要方向,含有无机和有机缓释氟源的树脂黏接剂的释氟效果已得到验证,其临床使用效果有待进一步研究。BACKGROUND：Demineralization of dental enamel is a complication in common after orthdontics treatment.The application of fluoride can inhibit the occurrence of demineralization of dental enamel and promote enamal remineralization.OBJECTIVE：To explore the mechanism and the application of fluoride in enamel adhesive in preventing enamel demineralization and reducing incidence of the enamel blazes after the treatment.METHODS：PubMed database from January 1990 to August 2010 was retrieved by computer with the Key words of＂fluoride release;enamel demineralization;enamel adhesive;orthdontics treatment＂in English.CNKI database from January 1990 to August 2010 was retrieved with the key words of＂fluoride release;enamel demineralization;enamel adhesive;orthdontics treatment＂ in Chinese.Literatures were limited to English and Chinese.Literatures concerning the development and clinical application of fluoride in enamel adhesive were included.RESULTS AND CONCLUSION：Hydroxy of Hhydroxyapatite unit cell was displaced by fluorine,the crystallinity,stability and hardness of apatite unit cell were enhanced.Fluorinion,calcium and phosphate ions in saliva constitute a mineralization system to improve the effect of enamal remineralization.The development of resin adhesive with slow-release fluorine source is an important direction to prevent demineralization of dental enamel.The effect of fluorine releasing in resin adhesive with inorganic and organic slow-release fluorine has been verified,and its clinical effect is need to be further studied.

关 键 词：牙釉质脱矿 氟化物 黏结剂 正畸治疗 相容性 

分 类 号：R318[医药卫生—生物医学工程]