新生BALB/c小鼠肠道潘氏细胞的分布规律  

The Pattern of Distribution of Paneth Cells in Intestine of Newborn BALB/c Mice

作　　者：王志峰[1] 梁宏德[1] 康静静[1] 张蕊[1] 杨玉荣[1] 

机构地区：[1]河南农业大学牧医工程学院,郑州450002

出　　处：《中国细胞生物学学报》2011年第7期772-776,共5页Chinese Journal of Cell Biology

基　　金：国家自然科学基金(No.30800812)资助项目~~

摘　　要：观察BALB/c小鼠小肠潘氏细胞的分布规律。应用石蜡切片、H&E染色技术和LeicaQwin显微图像处理系统,分别对2 d、4 d、6 d、8 d、10 d BALB/c小鼠小肠内潘氏细胞的形态发育、分布规律进行观察和分析。结果发现,4日龄前的BALB/c小鼠各段小肠中肠腺发育尚不完整,未见有潘氏细胞。6日龄后,潘氏细胞开始出现,数量随日龄增加呈递增趋势增长,各日龄间差异显著(P<0.05)。BALB/c小鼠肠道潘氏细胞存在于小肠,十二指肠和空肠较少,回肠较多,各组(不同日龄/肠段)之间差异显著(P<0.05)。To observe the regularity of distribution of Paneth cells in normal BALB/c mice, 2 d, 4 d, 6 d, 8 d, and 10 d BALB/c mice were selected respectively （n=3 in each group）. The distribution and morphology de- velopment of Paneth cells in different segments of the small intestines and different time were analyzed by paraffin section, HE staining and Leica microscopic image processing system. Result show that Paneth cells exist only in small intestine of the BALB/c mice, which is less in the duodenum and jejunum, and more in the ileum. The differ- ence among the different segments of the small intestines were statistically significant （P〈0.05）. 4 days before, the development of small intestine gland is not imperfect, and no Paneth cells were observed in it. After 6 days of birth, Paneth cells were found in small intestine gland. The difference among different ages and were statistically significant （P〈0.05）.

关 键 词：BALB/C小鼠 小肠 潘氏细胞 分布 

分 类 号：Q25[生物学—细胞生物学]