正常人股骨近端生物力学性能的区域性分析  

Biomechanics in Different Areas of Human Proximal Femur

作　　者：樊向利[1] 郭征[1] 宫赫[2] 石磊[1] 李小康[1] 王攀[1] 张涌泉[1] 袁超凡[1] 王军[1] 

机构地区：[1]第四军医大学西京骨科医院骨五科,陕西省西安市710032 [2]吉林大学机械科学与工程学院工程力学系

出　　处：《中国骨与关节损伤杂志》2011年第7期601-603,共3页Chinese Journal of Bone and Joint Injury

基　　金：国家高技术研究发展计划(编号2007AA03Z431)

摘　　要：目的分析股骨近端不同区域松质骨的显微结构及生物力学性能的差异性,为合理设计金属置入物提供力学参考。方法取7个新鲜正常人体股骨近端标本,进行Micro-CT扫描,分别对股骨头、股骨颈、粗隆间的骨小梁的结构参数进行分析,并结合大型有限元三维有限元对比分析各区域在主要受力方向上的生物力学性能。结果股骨头部的骨密度、骨矿含量、骨小梁密度、骨小梁数目明显高于股骨颈及粗隆间,差异有统计学意义(P<0.05),股骨颈与粗隆间相比则差异无统计学意义(P>0.05)。结论股骨近端不同区域的松质骨的显微结构及生物力学性能存在差异性,提示现有股骨近端金属置入物可能存在生物力学上的缺陷。Objective To analyze the cancellous bones micro-structure and biomechanical effects in different areas of proximal femur （head, neck and intertrochanter）,providing the mechanical parameters for metal implant. Methods Seven fresh moist human＇s proximal femur specimens were examined by Micro-CT, and the trabecular structure was assessed in the area of head, neck and intertrochanter re- spectively. Meanwhile, the biomechanical effects which were in the direction of the principal load were comparatively analyzed by large scale microfinite element analysis in the different areas. Results BMD,TMD and the elastic modulus showed the significant difference in the different areas of the proximal femur （head〉neck〉intertrochanter）. Conclusion The biological properties and biomechanical effects in different areas of proximal femur have significant difference, which should be considered in designing and manufacturing the femoral implant in the future.

关 键 词：股骨近端 有限元分析 生物力学 MICRO-CT 

分 类 号：R687.1[医药卫生—骨科学]