Effects of Acupuncture and Moxibustion on MDA, GSH-Px, and Hyp in the Skin of Senile Mice  

针灸对衰老模型小鼠皮肤中MDA、GSH-Px和Hyp影响的实验研究(英文)

作　　者：杨春英 徐斌 孙亦农 崔学军 

机构地区：[1]Laboratory of Combined Acupuncture and Drugs, Nanjing University of Traditional Chinese Medicine

出　　处：《Journal of Acupuncture and Tuina Science》2011年第3期142-144,共3页针灸推拿医学（英文版）

基　　金：National Key Laboratory Cultivation of the Laboratory on Combined Acupuncture and Medication,Higher Education of Jiangsu Province

摘　　要：Objective： To observe the effects of acupuncture and moxibustion on the skin histomorphology of senile mice. Methods： The subacute senile model of mouse was made by subcutaneous injection of D-galactose into the neck, then they were randomly allocated into an acupuncture group, a moxibustion group, a model group, and a blank group, and measured the content of malondialdehyde （MDA）, activity of glutathione peroxidase （GSH-Px）, and content of hydroxyproline （Hyp） in the skin tissue. Results： Acupuncture and moxibustion at Zusanli （ST 36） could decrease the content of MDA, enhance the activity of GSH-Px, and increase the content of Hyp in the skin tissue of senile mice. Conclusion： Acupuncture and moxibustion at Zusanli （ST 36） could delay the senescence progress of mice＇s skin.目的:观察针灸对衰老模型小鼠皮肤组织形态的影响。方法:长期颈背部皮下注射D-半乳糖造成小鼠亚急性衰老模型,随机分为针刺组、艾灸组、模型组和空白组,检测皮肤组织中丙二醛(Malondialdehyde,MDA)含量、谷胱甘肽过氧化物酶(Glutathione Peroxidase,GSH-Px)活力、羟脯氨酸(Hydroxyproline,Hyp)含量。结果:针灸足三里穴能够使衰老模型小鼠皮肤组织中的MDA含量减少,GSH-Px活力增强,Hyp含量增多。结论:针灸足三里穴对小鼠皮肤衰老具有拮抗作用。

关 键 词：Acupuncture-Moxibustion Therapy Points  ST 36 （Zusanli） Skin Aging MALONDIALDEHYDE Glutathione Peroxidase HYDROXYPROLINE 

分 类 号：R2-03[医药卫生—中医学]