骨碱性磷酸酶在佝偻病早期诊断中的应用  

Bone alkaline phosphatase in the early diagnosis of rickets

作　　者：刘英华[1] 潘炳灿 

机构地区：[1]菏泽医学专科学校临床医学系,274000 [2]菏泽市牡丹人民医院(菏泽医专附院)放射科,274000

出　　处：《中国实用医药》2011年第19期33-35,共3页China Practical Medicine

摘　　要：目的分析研究骨碱性磷酸酶(BALP)测定对维生素D缺乏性佝偻病早期诊断的临床意义。方法收集体检诊断为维生素D缺乏性佝偻病的0～3岁儿童520例,采用骨碱性磷酸酶(BALP)试剂盒进行检测,对比分析其中部分病例的血清钙磷及碱性磷酸酶含量。结果骨碱性磷酸酶早期诊断佝偻病阳性率达90.8%,与血清钙磷、ALP检测差异有统计学意义(P<0.01)。结论 BALP检测简便、快捷、特异性高、结果可靠、可减少漏诊率,对佝偻病早期诊断具有重要的指导价值,基层医院应推广。Objective Analysis of bone alkaline phosphatase（BALP）determination and clinical significance in vitamin D deprivation rickets.Methods Collected medical diagnosis of vitamin D deficiency rickets in children aged between 0 and 3 years old, 520 cases which had been measured the amount of BALP in their blood with bone alkaline phosphatase kit.Calcium and phosphorus, and alkaline phosphatase in serum were analyzed in some cases.Results Early diagnosis of rickets, bone alkaline phosphatase-positive rate of 90.8%, and serum calcium and phosphorus, ALP detected significant differences（P〈0.01）.Conclusion BALP test is simple, fast, highly specific, reliable, and can reduce the misdiagnosis rate of early diagnosis of rickets important guiding values, primary hospitals should be promoted.

关 键 词：骨源性碱性磷酸酶 维生素D 佝偻病 早期诊断 

分 类 号：R723[医药卫生—儿科]