颅脑损伤并发中枢性低钠血症的诊治体会  

Diagnosis and treatment of craniocerebral injury with central hyponatremia

作　　者：马兴才 黄云波 闭礼乐 

机构地区：[1]广西南宁市第七人民医院,广西南宁530012

出　　处：《海南医学院学报》2011年第8期1043-1045,共3页Journal of Hainan Medical University

基　　金：海南医学院科研基金资助学报项目(0020110263)~~

摘　　要：目的:分析总结颅脑损伤并发中枢性低钠血症的临床特点与病因,对其发病机制与诊断治疗进行探讨。方法:对我院2000年1月～2009年12月收治的86例颅脑损伤并发中枢性低钠血症患者的临床资料进行回顾性分析。结果:86例患者中出现脑性盐耗综合症(CSWS)的患者有62例,出现抗利尿激素异常分泌综合征(SIADH)患者24例。70例患者的低钠血症得到了良好的纠正,治愈时间在2～4周,此外有16例由于发生重度颅脑损伤,导致脑功能衰竭死亡。结论:对颅脑损伤合并中枢性低钠血症患者的血钠浓度需密切监测,且对于SIADH与CSWS的病因,发病机制及其相应需采取的治疗方法都是有所不同的,因而及时诊断有利于预后的改善,同时降低死亡率。Objective： To analyze clinical characteristics and causes of craniocerebral injury with central hyponatremia, and to discuss diagnosis and treatment. Methods： The clinical data of 86 patients with craniocerebral injury and central hyponatremia admitted from January 2000 to December 2009 were retrospectively analyzed. Results： Out of 86 patients, 62 had cerebral salt wasting syndrome （CSWS）, 24 had abnormal antidiuretic hormone secretion syndrome （SIADH）. 70 cases with hyponatremia were corrected, with cure time between 2-4 weeks. Another 16 cases with sever brain injury died due to brain failure. Conclusions： Close monitoring is important for patients with craniocerebral injury combined with central hyponatremia. CSWS and SIADH have different cause, and pathogenesis, and treatments are different, too. Thus timely diagnosis can improve the prognosis, and reduce mortality.

关 键 词：颅脑损伤 中枢性低钠血症 SIADH CSWS 

分 类 号：R651.15[医药卫生—外科学]