异丙醇羧酸铝催化合成呋喃酚反应研究  

Synthesis of Carbofuran Phenol by Aluminium Isopropoxide Carboxylate

作　　者：王宇[1,2] 罗先福[1] 胡艾希[1] 张建宇[1,2] 杨林涛[2] 

机构地区：[1]湖南大学化学化工学院,长沙410082 [2]湖南化工研究院,长沙410007

出　　处：《有机化学》2011年第7期1127-1130,共4页Chinese Journal of Organic Chemistry

基　　金：国家“863”计划课题(No.2006AA03Z460)资助项目

摘　　要：选择了异丙醇羧酸铝催化2-(2-甲基烯丙氧基)苯酚合成呋喃酚;探讨异丙醇羧酸铝用量对合成呋喃酚反应的影响.实验结果表明,异丙醇羧酸铝可高效催化2-(2-甲基烯丙氧基)苯酚合成呋喃酚.当催化剂为异丙醇二乙酸铝,用量为2-(2-甲基烯丙氧基)苯酚的2.50%(物质的量比),呋喃酚的收率达到80.8%,高于目前工业上以异丙醇铝为催化剂的78.3%,具有应用价值.Efficient synthesis of carbofuran phenol from 2-（2-methylallyloxy）phenol was achieved by using （RCO2）nAl（OPr-i）3-n as the catalysts. The effect of molar ratio of catalyst （RCO2）nAl（OPr-i）3-n-（2-methyllallyloxy）phenol on the yield was investigated. By employing （CH3COE）EAlOPr-i as the complex catalyst, the yield of carbofuran phenol was improved to 80.8%, which was higher than that of 78.3% in commercial installation.

关 键 词：异丙醇羧酸铝 呋喃酚 CLAISEN重排 环合 

分 类 号：TQ251.1[化学工程—有机化工]