多索茶碱治疗急性加重期慢性阻塞性肺疾病的临床观察  

Clinical observation of doxofylline in the treatment of acute exacerbation of chronic obstructive pulmonary disease

作　　者：张浩[1] 胡承志[2] 邹尔斌 王晓峰[1] 

机构地区：[1]中铁四局集团中心医院,安徽合肥230023 [2]合肥市第一人民医院,安徽合肥230061

出　　处：《临床肺科杂志》2011年第8期1174-1175,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察多索茶碱治疗慢性阻塞性肺疾病急性加重期(AECOPD)的临床疗效。方法选择AECOPD患者85例,随机分为多索茶碱组(治疗组)44例和氨茶碱组(对照组)41例,观察两组患者治疗前后症状、体征及肺功能变化。结果两组治疗前后临床症状、呼吸困难评分和肺功能等比较,差异有统计学意义(P<0.05)。结论多索茶碱治疗AECOPD能迅速缓解症状,畅通气道,改善肺功能,是治疗AECOPD的有效选择。Objective To study the effect of doxofylline in treatment of patients with acute exacerbation of chronic obstructive pulmonary disease.Methods There were 85 cases of AECOPD patients who were divided into treatment group（44 cases）and control group（41 cases） at random.Doxofylline and aminophylline were given.The changes of clinical manifestations and lung function were observed before and after the treatment.Results The differences in clinical manifestations,dyspnea scores and lung function were statistically significant between before and after the treatment（P0.05）.Conclusion Doxofylline can rapidly relieve symptoms of AECOPD,smoothing airway and improving lung function.It is an effective choice in treatment of patients with AECOPD.

关 键 词：慢性阻塞性肺疾病 多索茶碱 呼吸困难评分 肺功能 治疗 

分 类 号：R563.9[医药卫生—呼吸系统]