酮咯酸氨丁三醇复合芬太尼用于胸科手术术后镇痛的观察  

Observation of effects of three alcohol butyl ketorolac ammonia combined fen thoracic surgery for pain relief

作　　者：李红新[1] 詹锦六[1] 劳燕萍[1] 

机构地区：[1]广州市胸科医院麻醉科,广东广州510095

出　　处：《临床肺科杂志》2011年第8期1188-1189,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的观察酮咯酸氨丁三醇复合芬太尼用于胸科手术的镇痛效果。方法择期行胸科手术患者75例,随机分为A、B、C三组,术毕行PC IA镇痛。A组镇痛药物为酮咯酸氨丁三醇4 mg/kg,B组为酮咯酸氨丁三醇3 mg/kg、芬太尼4 ug/kg,C组为芬太尼10ug/kg,均用0.9%生理盐水稀释至100m l。记录0、8、16、24h VAS评分及不良反应。结果术后0 h A、B组评分低于C组(P<0.05);术后8、16、24h B组C组评分低于A组(P<0.05);A、B组术后24h出现不良反应例数少于C组(P<0.05)。结论酮咯酸氨丁三醇复合芬太尼用于胸科手术后PCIA效果良好,降低了芬太尼所致不良反应的发生率。Objective Observation of effect of pain relief using three alcohol butyl ketorolac ammonia in thoracic surgery.Methods 75 cases of thoracic surgery were selected,randomly divided into groups A、B、C,for the PCIA analgesia.Group A used analgesic drugs of three alcohol butyl ketorolac ammonia 4 mg/kg,Group B three alcohol butyl as ketorolac ammonia 3 mg/kg,and fentanyl in 4ug/kg,and Group C for 10 ug/kg fentanyl,all being diluted with saline 0.9% to 100 ml.Recorded measures were measured at the intervals of 0h,8h,16h,24h,and visual analog scores of pain and adverse reactions were observed.Results For zero hour after the surgery,Group A and Group B showed lower scores than Group C（P0.05）;At the intervals of 8 hours after the surgery,16 hours and 24-hour,Group B and Group C-VAS scores were lower than Group A（P0.05）;24h after the surgery,Group A and B showed less adverse reactions than Group C（P0.05）;Conclusion Three-alcohol butyl ketorolac ammonia compound fentanyl PCIA after thoracic surgery has good effect,and it reduces fentanyl-induced incidence of adverse reactions.

关 键 词：酮咯酸氨丁三醇 芬太尼 术后镇痛 

分 类 号：R614[医药卫生—麻醉学]