超声辐射下合成N'-三氮唑-N-取代苯氧乙酰基硫脲  

Synthesis of N'-triazolyl-N-substituted Phenoxyacetyl Thioureas Under Ultrasound

作　　者：李淑贤[1] 李雅[1] 许文峰[1] 申利红[1] 

机构地区：[1]邯郸学院化学系,河北邯郸056005

出　　处：《河北大学学报（自然科学版）》2011年第4期397-400,共4页Journal of Hebei University(Natural Science Edition)

基　　金：河北省科技计划项目(10276105D-102);邯郸市科学技术研究与发展计划项目(0923107101-8)

摘　　要：为给药物筛选提供先导化合物,利用超声波与相转移催化联用技术,合成了3个N-三氮唑-N-取代苯氧乙酰基硫脲衍生物,其结构经元素分析,IR和1H NMR进行了表征.该法具有操作简单、反应时间短等优点.初步的生物活性测试表明:部分化合物具有一定的除草活性.Three new N-triazolyl-N＇-substituted phenoxyacety thioureas were designed and synthesized by combined technique of ultrasonic irradiation and phase transfer catalysis. The structures of target compounds were characterized by elemental analysis, IR and^1 H NMR. The synthetic method has the advantages of simple operation and short time. The preliminary biological test shows that some of compounds have some inhibitory against weeds.

关 键 词：酰基硫脲 三氮唑 超声辐射 

分 类 号：O621.392[理学—有机化学]