2型糖尿病患者24h尿微量白蛋白相关因素分析及临床意义  

Analysis of related factors in 24 hours urine microalbumin in patients with type 2 diabetes

作　　者：闫忠卿[1] 韩丽萍[1] 谢云[1] 

机构地区：[1]天津医科大学代谢病医院糖尿病神经内科,天津300070

出　　处：《吉林医学》2011年第19期3867-3868,共2页Jilin Medical Journal

摘　　要：目的:筛查2型糖尿病患者(T2DM)24 h尿微量白蛋白(24 h UMA)相关因素,以期进一步指导2型糖尿病患者肾病预防和治疗。方法:测定住院的2型糖尿病患者的体重,血生化如肾功能、血脂等,尿生化如24 h尿微量白蛋白等,计算BMI,肾小球滤过率、肌酐清除率,晨尿微量白蛋白/肌酐。结果:24 h尿微量白蛋白与体重、BMI、血肌酐、血尿素氮、24 h尿总蛋白、24 h尿肌酐、晨尿微量白蛋白、微量白蛋白/肌酐、TC、LDL、收缩压均有相关性,与HbA1c、FMN无相关性。结论:24 h尿微量白蛋白反映糖尿病肾脏病变,控制肾病要作好体重、血脂、收缩压的控制,血糖控制不宜过严。Objective To analyze the factors affecting 24 hours urine microalbumin（UMA）in patients with type 2 diabetes,further to guide the clinic.Method To measure the weight and the blood items sush as creatinine and urine items such as 24 hours UMA,to account some items such as BMI,filterableness of renal glomerulus.Results 24 hours UMA was correlated with weight,BMI,blood creatinine,blood urea nitrogen,24 hours urine total protein（TP）,24 hours urine creatinine,urina sanguinis microalbumin,urina sanguinis microalbumin/urina anguinis creatinine,TC,LDL,SBP.And there was no relationship between 24 hours UMA with HbA1c,FMN.Conclusion 24 h UMA indicates pathological change of kidney,and to prevent from diabetic nephropathy（DN）,we should control weight,blood fat,SBP,but the blood sugar is not the lower the better.

关 键 词：24小时尿微量白蛋白 糖尿病糖尿病肾病 相关性 

分 类 号：R587.2[医药卫生—内分泌]