瑞巴派特的HPLC测定  

HPLC DETERMINATION OF REBAMIPIDE

作　　者：李悦[1] 

机构地区：[1]上海医药工业研究院,上海200040

出　　处：《中国医药工业杂志》1999年第12期546-548,共3页Chinese Journal of Pharmaceuticals

摘　　要：采用ＨＰＬＣ测定瑞巴派特含量及其杂质。色谱柱为ＹＷＧ Ｃ１８ ，流动相为甲醇－ｐＨ ６．５ 磷酸盐缓冲液（含１％ 氢氧化四丁基铵的１０％ 水溶液）（５２∶４８）。方法简便、结果准确。Rebamipide and its impurities were separated on YWG C 18 column with methanol phosphate buffer solution (52∶48) as mobile phase, which contained tetrabutyl ammonium salt and was adjusted to pH6.5. The method is simple, sensitive, selective and accurate.

关 键 词：瑞巴派特 高效液相色谱 测定 溃疡病用药 

分 类 号：R975.6[医药卫生—药品] R927.2[医药卫生—药学]