2004-2010年娄底市丙型病毒性肝炎流行病学分析  

Epidemiological Analysis of Hepatitis C in Loudi During the Period of 2004～2010

作　　者：王健龙[1] 胡东风[1] 吴笃卿[1] 傅永安[1] 钟琳[1] 袁利和[1] 吴幂[1] 张志刚 阙魏 李玉圆[1] 阳丽芳[1] 

机构地区：[1]湖南省娄底市疾病预防控制中心,湖南娄底417000 [2]娄底市中心血站

出　　处：《实用预防医学》2011年第7期1249-1252,共4页Practical Preventive Medicine

摘　　要：目的分析娄底市丙肝的流行特征及吸毒人员和献血者HCV感染状况。方法通过中国疾病预防控制信息系统收集个案资料,以ELISA法检测吸毒人员和献血者抗-HCV,用Excel和SPSS进行数据分析。结果 2004-2010年共报告丙肝927例,年均发病率3.46/10万,发病率呈逐年上升趋势,年均增长220.36%。各县市区年均发病率差异有统计学意义,城区明显高于乡镇(P<0.01)。全年呈散发状态,无明显季节高峰。患者男女性别比为1.48:1,青壮年和中老年人发病率明显高于儿童和青少年,离退休人员发病率为最高。吸毒人员和献血者抗-HCV阳性率分别为68.77%和0.51%,各年龄组阳性率差异无统计学意义,但注射吸毒者HCV阳性率显著高于口服吸毒者。结论近年来娄底市丙肝发病率呈快速上升趋势,已成为严重的公共卫生问题之一。吸毒者、农民和离退休人员是丙肝防控应关注的重点人群,注射吸毒是丙肝感染最重要的高危因素。Objective To analyze the epidemiological profiles of hepatitis C in Loudi from 2004 to 2010,and to survey the infectious status of HCV in drug users and blood donors in the city.Methods Descriptive epidemiological analysis was conducted on the data of hepatitis C obtained from China Information System for Diseases Control and Prevention,positive rates of anti-HCV in drug users and blood donors were detected by ELISA.The data were analyzed using Excel and SPSS softwares.Results A total of 927 hepatitis C cases were reported from 2004 to 2010,with an annual average incidence rate of 3.46/100,000.The incidence rate was increased year after year,with an annual increase of 220.36%.The incidence rates of urban districts was significantly higher than those of rural areas and towns（P0.01）,there were statistically signifi cant differences among the incidence rates of different districts/counties.Sporadic cases were reported all the year round without obvious seasonal peaks.Male to female ratio for patients with hepatitis C was 1.48：1.The incidence rates of young adults and middle-aged and elderly persons were significantly higher than that of children and teenagers,and that of retirees was highest.The positive rates of anti-HCV in drug users and blood donors were 68.77% and 0.51%,respectively.No statistically significant difference was found in the positive rate of anti-HCV among the different age groups.But the positive rate of anti-HCV in injection drug users was significantly higher than that of oral users.Conclusions The rapid increased incidence of hepatitis C in Loudi has become one of the most important public health problems.Drug users,farmers and retirees are the focus group which should be paid attention to in the control and prevention of hepatitis C,and injection drug users are the most important risk factor of hepatitis C infection.

关 键 词：丙型肝炎 流行特征 抗-HCV 

分 类 号：R181.8[医药卫生—流行病学]