前列腺特异性抗原检测在前列腺疾病中的临床应用  

Clinical Application of Prostate-specific Antigen Detection in Prostate Diseases

作　　者：杨望君 潘美秋 

机构地区：[1]湖南省岳阳市三人民医院检验科,湖南岳阳414000 [2]岳阳市二人民医院检验科

出　　处：《实用预防医学》2011年第7期1341-1342,共2页Practical Preventive Medicine

摘　　要：目的探讨血清前列腺特异性抗原(PSA)在前列腺疾病诊断中的意义。方法采用放射免疫法对健康对照组60例、前列腺良性疾病组82例、前列腺癌组53例进行血清PSA测定,并对前列腺癌患者手术前后血清PSA测定比较其差异。结果前列腺癌组t-PSA、f-PSA和f-PSA百分率测定结果均明显高于对照组,差异有统计学意义(P<0.01),前列腺癌患者手术前后血清t-PSA、f-PSA和f-PSA百分率比较,差异有统计学意义(P<0.01)。结论血清PSA检测在前列腺疾病诊断中有重要意义,是疗效监测、评估预后的重要指标。Objective To explore the serum prostate specific antigen（PSA） in the diagnosis of prostate diseases.Methods Serum PSA levels of healthy control group（n=60）,benign prostate disease group（n=82）,and prostate cancer group（n=53） were detected by radioimmunoassay method.And the difference in serum PSA levels of prostate cancer patients was compared before and after the operation.Results The determination results showed that serum t-PSA,f-PSA and percentage of f-PSA in prostate cancer group were significantly higher than those in healthy control group,and the difference was statistically significant（P0.01）.There were statistically significant differences in serum t-PSA,f-PSA and percentage of f-PSA of prostate cancer patients between before and after the operation（P0.01）.Conclusions It is of great significance to detect serum PSA level in the diagnosis of prostate diseases,which is an important indicator in monitoring the therapeutic effect and evaluating the prognosis.

关 键 词：前列腺癌 前列腺特异性抗原 放射免疫分析 

分 类 号：R697.3[医药卫生—泌尿科学]