人胚胎视皮质神经元发育的体视学分析  

STEREOLOGICAL QUANTITATIVE ANALYSIS OF NEURON DEVELOPMENT IN VISUAL CORTEX OF HUMAN FETUS

作　　者：纳冬梅 王荣华[2] 孙强[2] 宋铁军 

机构地区：[1]内蒙古包头市包钢职工医院神经内科,包头014010 [2]哈尔滨医科大学组织学与胚胎学教研室

出　　处：《解剖学杂志》1999年第6期529-533,共5页Chinese Journal of Anatomy

摘　　要：实验取自１４例产后死亡的胎儿，胎龄１２～４０周，对其视皮质神经元进行电镜观察及立体计量分析。结果表明：（１）视皮质神经元在发育早期（１２周胎龄）时，可依细胞大小、核及胞质中的细胞器鉴别神经元和神经胶质细胞；（２）视皮质神经元发育过程中，核质比例逐渐减小，细胞核体密度逐渐减少，核仁与胞质的体密度呈上升趋势（３）线粒体、粗面内质网、核糖体的体密度呈明显上升趋势，滑面内质网、高尔基复合体及溶酶体的体密度也有不同程度的上升。Neurons in the visual cortex derived from 14 normal fetuses (postpartum death) aged from 12-40 weeks were observed under electron microscope and analysed stereologically. The results were as follows: 1. At the early stage of the human fetus development (12 weeks), the neurons and neuroglial cells could be discriminated by cell size, nucleus and organelle of cytoplasm. 2. In the development of nuerons in the visual cortex, nucleopasmic index and NP decreased with time. 3. The volume density of nucleus decreased with the time of development, but the volume density of nucleolus and cytoplasm increased. 4. The volume density of mitochondria, rough endoplasmic reticulum and ribosome significantly increased and the volume density of smooth endoplasmic reticulum, Golgi complex and lysosome increased in various degrees.

关 键 词：视皮质神经元 发育 胚胎 体视学 

分 类 号：R321[医药卫生—人体解剖和组织胚胎学]