继发全身强直-阵挛发作的病毒性脑炎患者的临床分析  

Clinical analysis in viral encephalitis patients accompanying generalized tonic clonic seizure

作　　者：张文洛[1] 彭朝胜[1] 夏菁[1] 田力[1] 杨璐[1] 康怡[1] 谢文秀[1] 曹悦鞍[1] 

机构地区：[1]海军总医院特需医疗部,北京100048

出　　处：《中华实验和临床病毒学杂志》2011年第3期217-219,共3页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的 总结继发全身强直-阵挛发作（Generalized tonic clonic seizure,GTCS）的病毒性脑炎患者的临床表现、脑脊液、影像及脑电图（EEG）检查对诊断的价值.方法 回顾性分析30例继发GTCS的病毒性脑炎患者的临床表现、脑脊液、影像学特征及EEG改变.结果 30例病毒性脑炎患者,发病2周内出现GTCS者21例（70%）,发病15-28 d出现GTCS者9例（30%）;27例患者脑脊液检查,主要异常表现为压力、细胞数、蛋白增高,脑脊液病原学检查阳性率为12/16;19例（63.3%）头颅MR1异常;患者发病初期EEG均出现异常.结论 患者的临床表现、影像学表现及EEG检查对病毒性脑炎合并癫痫患者的诊断、继发GTCS的评估具有重要作用.Objective To summarize the value of clinical features, CSF, imaging and EEG in diagnosing viral encephalitis accompanying generalized tonic clonic seizure（ GTCS） . Methods The clinical, imaging and EEG characteristic of 30 patients with viral encephalitis accompanying GTCS were retrospectively analyzed. Results Of the 30 cases with viral encephalitis,21 cases GTCS attacked（70% ） within 14 days,9 cases had GTCS （30% ） in 15-28 days.27 cases CSF were abnormal with the pressure,cell number,protein. The incidence of positive pathogenicity was 12/16; 19 cases MRI had abnormal signal. All the patients had abnormal EEG during the disease. Conclusion The clinical features, CSF, imaging and EEG were all important in diagnosing and estimate of viral encephalitis accompanying GTCS.

关 键 词：脑炎 病毒性 癫痫 强直阵挛性 

分 类 号：R51[医药卫生—内科学]