原发干燥综合征45例临床分析  

Clinical features of primary Sjgren's syndrome:analysis on 45 cases

作　　者：张佩莲[1] 王文芳[1] 贺小洁[2] 李晓岚[1] 邓丹琪[1] 付萍[1] 周晓鸿[1] 郭芸[1] 谢红[1] 王晓云[1] 姜福琼[1] 冒长峙[1] 

机构地区：[1]昆明医学院第二附属医院皮肤性病/风湿科,云南昆明650101 [2]昆明医学院第二附属医院呼吸科,云南昆明650101

出　　处：《临床皮肤科杂志》2011年第8期461-463,共3页Journal of Clinical Dermatology

摘　　要：目的:分析原发性干燥综合征(pSS)的临床特征,旨在提高对该病的诊治水平。方法:回顾性分析该院住院诊治的45例pSS患者的临床特点。结果:成人发病者首发症状表现多样化,常见的有口眼干燥、关节疼痛、淋巴结肿大、血小板减少、腮腺肿大、发热及皮肤表现等。结论:pSS的首发症状多样化,易误诊、漏诊,仔细询问病史并进行自身抗体等相关检查是避免误诊的关键。Objective： To improve the level of diagnosis and management of primary Sjogren＇s syndrome （PSS） through studying the clinical features of the disease. Methods： Clinical data of 45 in-patients with PSS were retrospectively reviewed. Results： In adult patients, initial clinical symptoms were various, such as dry mouth and eyes, arthralgia, lymphadenopathy, thrombocytopenia, parotid gland swelling, fever, and skin rashes which were more common. The positivity of serum rheuma- toid factor, anti-SSA and anti-SSB antibodies, and increased level of serum IgG level were also more common in the adult patients. Conclusion： The clinical characteristics of PSS patients are various. It is critical to have a detailed history of the patients and check related auto-antibodies so as to avoid misdiagnosis.

关 键 词：干燥综合征 临床特点 

分 类 号：R442.8[医药卫生—诊断学]