超声心动图对慢性肺血栓栓塞症患者左室偏心指数的相关分析  

Correlation Analysis of Left Ventricular Eccentricity Index and Pulmonary Artery Hypertension in Chronic Pulmonary Thromboembolism Patients by Echocardiography

作　　者：李召琴[1] 吴雅峰[1] 刘晓伟[1] 杨媛华[2] 王辰[2] 

机构地区：[1]首都医科大学附属北京朝阳医院超声医学科,北京市100020 [2]首都医科大学附属北京朝阳医院呼研所科,北京市100020

出　　处：《中国超声医学杂志》2011年第7期628-631,共4页Chinese Journal of Ultrasound in Medicine

基　　金：国家“十一五”科技支撑计划项目(No.2006BAI01A06)

摘　　要：目的探讨慢性肺血栓栓塞症(CPTE)患者肺动脉高压程度与左室偏心指数(EI)相关性。方法对本院确诊的85例CPTE患者行超声心动图检查,根据肺动脉收缩压分为4组(压力正常为组1、轻度增高为组2、中度增高为组3、重度增高为组4)。对压力增高组与压力正常组的左室EI分别进行相关性分析。结果随着肺动脉压增高,左室EI增大,(组间比较,P=0.009),肺动脉压与左室EI呈线性高度相关。与左室舒张早期受损明显相关。随CPTE肺动脉压力增高,右室扩大、右室肥厚、右室壁运动明显减低,右室射血分数减低(组间比较P<0.001)。结论 CPTE患者肺动脉高压及右室负荷增高,左室EI增加,左室EI是评价右心负荷程度和肺动脉高压显著增高的重要指标。Objective To evaluate the association of the pulmonary artery hypertension with left ventricular ec centricity index（EI） in patients with chronic pulmonary thromboembolism（CPTE）. Methods Eighty-five patients with chronic pulmonary thromboembolism were divided into four groups according to the pulmonary artery systolic pressure （PASP） estimated by echocardiography： normal pressure group; mild increased PASP group; moderate increased PASP group; severe increased PASP group. We analyzed the association of the EI in increased pressure group and the normal pressure group. Results Left ventricular EI increased with the raised pulmonary artery pressure（P= 0. 009）, EI significantly linear correlated with PASP and early left ventricular diastolic dysfunction. With the chronically increased pulmonary pressure, the right ventricle enlarged and thickened, right ventricular wall motion obviously reduced, and also right ventricular ejection fraction decreased（P〈0. 001）. Conclusions Pulmonary artery hypertension of CPTE can results in right ventricleOverload and left ventricular EI increasing. Left ventricular EI is an important index in assessment of the right heart overload and pulmonary artery hypertension.

关 键 词：超声心动图 慢性肺血栓栓塞 左室偏心指数 

分 类 号：R540.45[医药卫生—心血管疾病] R563.5[医药卫生—内科学]