A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support  

作　　者：Meng Gao Cui Fen Lu Gui Chun Yang Zu Xing Chen 

机构地区：[1]Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecule & School of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China

出　　处：《Chinese Chemical Letters》2011年第7期823-826,共4页中国化学快报（英文版）

基　　金：the Natural Sciences Foundation of Hubei province in China(Nos.2007ABA031 and 2008CDA078)

摘　　要：In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-aryl-2,5- dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products were cleaved from the supports and obtained in good yields.In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-aryl-2,5- dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products were cleaved from the supports and obtained in good yields.

关 键 词：Onium salt SUPPORT Synthesis PYRIDAZINES 

分 类 号：O633.22[理学—高分子化学] TB383[理学—化学]