Correlation between CD4^＋CD25^＋Treg Cells and CCR4 in Nasopharyngeal Carcinoma  

作　　者：Yan-xin REN Jun SUI Xin SONG Gee WAN WONG Jing MA Hong YAO Marie Chia-mi LIN Xiao-jiang LI 

机构地区：[1]Immunotherapy Center, The ThirdAffiliated Hospital, Kunming MedicalCollege, Kunming 650118, Yunnan Province,China. [2]Head and Neck Surgery, The Third AffiliatedHospital, Kunming Medical College,Kunming 650118, Yunnan Province, China. [3]Institute of Molecular Biology, Departmentof Chemistry, Open Laboratory of ChemicalBiology, The University of Hong Kong, HongKong, China.

出　　处：《Clinical oncology and cancer researeh》2011年第2期106-113,共8页

基　　金：the National Natural Science Foundation of China

摘　　要：OBJECTIVE CD4^＋CD25^＋ T regulatory （Treg） cells are a population of T cells which suppress an overactive immune system. CCR4 is a chemokine receptor involved in the recruitment of lymphocytes. Nasopharyngeal carcinoma （NPC） is resistant to immunosurveillance, owing to the increased number of tumor-infiltrating Treg cells which are recruited to the tumor bv CCR4.

关 键 词：nasopharyngeal carcinoma CD4^＋CD25^＋ Treg cells CCR4 flow cytometry tumor-infiltrating lymphocytes. 

分 类 号：Q954.43[生物学—动物学] X51[环境科学与工程—环境工程]