血浆B型脑钠肽对心力衰竭和呼吸困难的诊断价值  

Value of Detection of Plasma Brain Natriuretic Peptides in Diagnosis of Congestive Heart Failure and Dyspnea

作　　者：栾和伟 徐天祥[1] 许馨[1] 张俊[1] 吴在荣 

机构地区：[1]句容市人民医院检验科,江苏句容212400

出　　处：《现代生物医学进展》2011年第15期2924-2925,2923,共3页Progress in Modern Biomedicine

摘　　要：目的:探讨血浆脑钠肽(BNP)水平在心力衰竭(CHF)T和呼吸困难诊断中的应用。方法:采用免疫荧光快速测试法测定56例已确诊心衰患者、40例心源性呼吸困难患者、29例肺源性呼吸困难患者和30例健康人血浆BNP的含量。结果:心衰组患者血浆BNP水平明显高于对照组,差异显著(P<0.01);心源性呼吸困难组患者的BNP值水平(1032.2±879.8 pg/ml)与肺源性呼吸困难组患者的BNP值水平(67.1±43.6 pg/ml)比较有显著性差异(P<0.01)。结论:检测BNP水平可为临床诊断CHF及心源性与肺源性呼吸困难的鉴别诊断提供重要依据。Objective： To investigate the value of detecting brain natriuretic peptides （BNP） level in diagnosis of congestive heart failure（CHF） and dyspnea. Methods： Plasma BNP was measured in 56 patients with CHF,40 cardiac dyspnea ,29 pulmonary dyspnea and 30 healthy subjects by immunofluorescence assays. Results： The level of BNP of the patients with CHF was significantly higher than that in healthy subjects,with significant difference （P〈0.01）. The level of BNP （1032.2 ± 879.8 pg/ml） in patients with cardiac dyspnea was significantly higher than that （67.1 ± 43.6 pg/ml） in pulmonary dyspnea （P〈0.01）. Conclusion： Detecting BNP is of great value for the clinical diagnosis of CHF and differential diagnosis between cardiac dyspnea and pulmonary dyspnea.

关 键 词：BNP 心力衰竭 呼吸困难 

分 类 号：R541[医药卫生—心血管疾病]