Delaying Vascular Aging with Chinese Medicine:Implications from An Overview of the p53 and miR-34s Family  

作　　者：王铭 雷燕 

机构地区：[1]Xiyuan Hospital,China Academy of Chinese Medical Sciences

出　　处：《Chinese Journal of Integrative Medicine》2011年第8期635-639,共5页中国结合医学杂志（英文版）

基　　金：Supported by National Natural Science Foundation of China (No.30973828);Major State Basic Research Development Program of China(937 P rogram,No.2007CB507400);Self-Project Foundation from China Academy of Chinese Medical Sciences(No.Z021 51)

摘　　要：p53 is an important target for studying vascular aging.However,as people gradually learned more about the miR-34s and the relationship between miR-34s and p53,new research idea emerged.This paper tries to elaborate the feature of p53,microRNA and miR-34s in-depth,analyze the regulatory action of miR-34s on p53,and offer some new prevention and treatment prospects about vascular aging in Chinese medicine.p53 is an important target for studying vascular aging.However,as people gradually learned more about the miR-34s and the relationship between miR-34s and p53,new research idea emerged.This paper tries to elaborate the feature of p53,microRNA and miR-34s in-depth,analyze the regulatory action of miR-34s on p53,and offer some new prevention and treatment prospects about vascular aging in Chinese medicine.

关 键 词：vascular aging P53 miR-34s Chinese medicine 

分 类 号：R259[医药卫生—中西医结合]