利用Wolbachia控制登革热传播的研究进展  

The advancement of researches on using Wolbachia to control the epidemic of dengue fever

作　　者：张东京[1] 詹希美[1] 郑小英[1] 

机构地区：[1]中山大学中山医学院寄生虫学教研室,广州510080

出　　处：《国际医学寄生虫病杂志》2011年第4期234-237,共4页International JOurnal of Medical Parasitic Diseases

摘　　要：沃尔巴克体（Wolbachia）是一类广泛存在于节肢动物中的革兰阴性共生菌，该菌对宿主生殖有多种调控能力，可以诱导细胞质不亲和（cytoplasmic incompatibility，CI）、孤雌生殖（parthenogenesisinducing，PI）、杀雄作用（male—killing）和雌性化（feminizing）等。近来研究发现Wolbachia对登革病毒的繁殖和传播有控制作用。该文对近年来Wolbachia在控制登革热传播过程的应用价值作一综述。Wolbachia is a gram-negative endosymbiotic bacterium, which widely exists in arthropods. The bacterium has several effects on controlling host＇s reproduction, that include inducing cytoplasmic incompatibility, parthenogenesis-inducing, male-killing and feminizing. The recent researches discovered that Wolbachia can control the multiplication and transmission of dengue virus. This review summarized the potential application of Wolbachia in controlling the epidemic process of dengue fever.

关 键 词：WOLBACHIA 生物控制 登革病毒 登革热 

分 类 号：R384.1[医药卫生—医学寄生虫学]