不同方法及溶剂对黄连小檗碱的提取效果比较  

Study on extraction of berberine in rhizoma of Coptis chinensis Franch by different solvents and different extracting ways

作　　者：席国萍[1] 宋国斌[1] 

机构地区：[1]山西大同大学医学院,山西大同037009

出　　处：《化学工程师》2011年第7期59-60,共2页Chemical Engineer

摘　　要：本文采用3种不同方法,分别以乙醇、丙酮、水作为提取溶剂对黄连小檗碱进行提取。以盐酸小檗碱作为对照,用标准曲线法测定各种溶剂及方法提取液中黄连小檗碱的提取率。实验结果表明:采用回流提取法,提取溶剂为乙醇,黄连小檗碱的提取率达到81%以上,标准偏差为0.0005,相对标准偏差为0.06%。Using ethanol,acetone,water as the solvents,the berberine in rhizoma of Coptis chinensis Franch was extracted by three different ways.The extraction rates of berberine in different extracting solvents and in different ways were detected by the standard curve method using hydrochloric acid berberine as the contrast.The experiment results showed： using ethanol and the back-flow extraction,the extraction rate of berberine in rhizoma of Coptis chinensis Franch was higher than 81% which S was 0.0005 and RSD was 0.06%.

关 键 词：黄连 小檗碱 提取 

分 类 号：R927.2[医药卫生—药学]