动态血压评价安博诺对中青年高血压治疗效果  

Ambulatory Blood Pressure Monitoring to Evaluate the Effect of Coaprovel in the Treatment of Young and Middle-Age Hypertensives

作　　者：刘腊平 

机构地区：[1]山西大同煤矿集团二医院内二科,山西大同322118

出　　处：《山西大同大学学报（自然科学版）》2011年第3期54-55,63,共3页Journal of Shanxi Datong University(Natural Science Edition)

摘　　要：目的评价复方制剂安博诺治疗中青年原发性高血压的效果及其对代谢的影响。方法未经药物治疗的中青年原发性高血压患者64例,每日服用安博诺(厄贝沙坦150 mg双氢克尿噻12.5 mg)1片,共4周,监测服药前后24 h动态血压和生化指标。结果服药后总有效率90.2%;治疗后24 h,白昼和夜间平均收缩压和舒张压与治疗前比较,差异有统计学意义,治疗前后生化指标无明显改变,未观察到严重不良反应。结论安博诺治疗中青年高血压有效,不良反应少。Objective To evaluate the effects of Coaprovel（Irbesantan 150 mg ＋hydro-chlorothiazide 12.5 mg tablet） in the treatment of young and middle-age hypertensives and its metabolic influence.Methods 64 patients were treated with coaprovel one tablet per day for 4 weeks and examined ambulatory blood pressure monitoring（ABPM） and measured blood glucose,lipid,unic acid,hepatic and renal function at the beginning and the ending of the treatment.Results After 4 week treatment the effective rate was totalled 90.2%.The ABPM of these patients containing 24 h daytime and nighttime average systolic and diastolic pressure were more lower than those before treatment,this lowered degree was very significantly.As to the value of blood glucose,lipid,unic acid.hepatic and renal function measuring at the ending of the treatment also preserved no obviously change.Conclusions The Irbesantan compound drug（Coaprovel） is considered to be satisfactorily Security for the treatment of young and middle-age hypertensives.

关 键 词：安博诺 中青年高血压 24H动态血压 

分 类 号：R544.1[医药卫生—心血管疾病]