莪术挥发油提取工艺的研究  

Study on the Extraction of Rhizoma Curcumae

作　　者：夏超[1] 马健 刘媛[1] 石金城[1] 孙兴华[3] 林本青[3] 樊明[3] 

机构地区：[1]江苏南京工业大学(江苏省药物研究所有限公司),江苏南京210009 [2]中国水利水电第十三工程局职工医院药械科,山东济南253009 [3]江苏南京工业大学,江苏南京210009

出　　处：《中国医药指南》2011年第21期20-21,共2页Guide of China Medicine

摘　　要：目的利用正交设计优选法确定提取莪术挥发油的最佳工艺条件。方法以莪术油的含量为指标,通过L9(34)正交试验设计,对提取工艺中的浸泡时间、提取时间、加水量和药材粒度4个因素进行优选研究,以筛选出莪术挥发油的最佳提取工艺条件。结果影响提取的主次因素为:提取时间>药材粒度>浸泡时间>加水量。优选得到的最佳提取工艺条件是浸泡12h,提取5h,加水7倍,药材粒度为粒状。结论本工艺条件科学合理,稳定可行,可有效保证产品质量。Objective To optimize the optimum extracting process of Rhizoma Curcumae by orthogonal design.Methods An orthogonal design table L 9（3^4）was used with the factors of soaking time;extraction time;water-adding amount and medicinal size.Results The factors influencing the extraction efficiency were as follows：extraction time〉medicinal size〉soaking time〉water-adding amount.The optimum extraction condition obtained was soaking 12 hours,extraction time 5 hours,7 folds of the materials weight and size for the granular medicine.Conclusion The optimized process is scientific and reasonable,which could guarantee the quality of product effectively.

关 键 词：莪术 提取 正交设计 

分 类 号：R282.710.2[医药卫生—中药学]