邻氯苯乙腈水解合成邻氯苯乙酸  

The Synthesis of o-c hlorophenylacetic Acid by Hydrolysis of o-c hlorophenylacetonitrile

作　　者：刘鑫[1] 刘建庄[1] 

机构地区：[1]娄底师范高等专科学校化生系,湖南娄底417000

出　　处：《娄底师专学报》1999年第4期96-98,共3页Journal of Loudi Teachers College

摘　　要：邻氯苯乙腈水解制邻氯苯乙酸 ,在以硫酸、水、乙酸按体积比 1∶1∶1的混合酸催化下 ,反应时间 80min ,回流温度 12 0℃ ,可获 86.2 %的收率 .o-o hlorophenylacetic acid can be synthesized by hydrolysis of o-c hlorophenylacetonitrile under the catalysis of mixture which is got according to the same volumes proportion of sulfuric acid,water and acetic acid.The yield-was 86.2% when the reaction time was 80 minutes and the reaction temperature was 120℃.

关 键 词：邻氯苯乙腈 邻氢苯乙酸 水解 合成 消炎镇痛药 

分 类 号：O625.511[理学—有机化学] TQ463.4[理学—化学]