米非司酮与去氧孕烯炔雌醇治疗功能失调性子宫出血的疗效比较  

作　　者：管付娟 

机构地区：[1]公安县人民医院,湖北荆州434300

出　　处：《求医问药（下半月刊）》2011年第7期223-223,共1页Seek Medical and Ask The Medicine

摘　　要：目的:比较米非司酮与去氧孕烯炔雌醇治疗功能失调性子宫出血(功血)的临床疗效。方法:随机将68例患者分为米非司酮组(n=34)和去氧孕烯炔雌醇组(n=34),对两种治疗方法的临床疗效进行比较研究。结果:在34例米非司酮组患者中,有25例患者在停药30—120 d后月经量恢复正常;6例患者的月经量出现减少,3例月经恢复后,出现功血复发。而在34例去氧孕烯炔雌醇组患者中,27例患者治疗期间无异常出血,停药后月经量恢复正常,随访期间无异常。两组临床疗效无明显差异(P>0.05)。另外,对两组患者治疗前后的血清激素水平比较发现,去氧孕烯炔雌醇组、米非司酮组两组患者治疗后E2、P平均水平均较本组治疗前明显降低(P<0.05)。结论:米非司酮和去氧孕烯炔雌醇均能有效治疗功能失调性子宫出血,且疗效无显著差异,不良反应均较轻微,复发率低,是两种比较理想的药物治疗方案。Goal：The alkone and the deacidizing are pregnant the alkene ethinyloestradiol treatment function rheomalaxis uterine hemorrhage compared with Mi Feisi（merit blood） the clinical curative effect.Method;Divides into stochastically 68 example patients Mi Feisi the alkone group（n=34） and the deacidizing is pregnant the alkene ethinyloestradiol group（n=34）,carries on to two kind of method of treatments clinical curative effect quite studies.Finally：In 34 example Mi Feisi in the alkone group patients,some 25 example patient after stopping medicine 30 - 120 d the volume of menstrual flow restores normally;6 example patients volume of menstrual flow presents the reduction, after 3 example menstruations restore,presents the merit blood recrudescence.But in 34 example deacidizings are pregnant in the alkene ethinyloestradiol group patients,27 example patients treat the period does not have exceptionally bleeds,after stopping the medicine, the volume of menstrual flow restores normally,revisit period does not have exceptionally.Two group of clinical curative effect not obvious differences（P0.05）.Around moreover,treats to two group of patients the blood serum hormone level quite to discover that before after the deacidizing is pregnant the alkene ethinyloestradiol group,Mi Feisi the alkone group two group of patients treats,E2,P average water mean difference this group of treatments,to reduce（P obviously

关 键 词：米非司酮 去氧孕烯炔雌醇 功能失调性子宫出血 

分 类 号：R711.52[医药卫生—妇产科学]