血栓性血小板减少性紫癜6例临床分析  

Clinical analysis of 6 patients with thrombotic thrombocytopenic purpura

作　　者：韦夙[1] 黄锦雄[1] 叶红[1] 

机构地区：[1]柳州市人民医院血液科,广西柳州545006

出　　处：《华夏医学》2011年第3期309-312,共4页Acta Medicinae Sinica

摘　　要：目的:探讨血栓性血小板减少性紫癜(TTP)的早期诊断及治疗方法,提高对本病的认识。方法:回顾性分析6例TTP患者住院病历资料。结果:6例患者均有血小板减少、微血管病性溶血性贫血(MAHA)、明显精神神经症状。6例患者均采用血浆置换(PE),联用肾上腺糖皮质激素和抗血小板药物等综合治疗。4例存活,2例死亡。结论:TTP临床表现不完全具有五联征,早期诊断指标是血小板减少和微血管病性溶血,及时行血浆置换联合糖皮质激素治疗是提高TTP治疗成功率的有效方法。Objective：To evaluate the early diagnosis and treatment of thrombotic thrombocytopenic purpura（TTP）. Methods. The clinical data of 6 patients with TTP was retrospectively analyzed. Results： 6 patients showed the trilogy of plate-reduction hemorrhage,microangiopathic hemolytic anemia and nervous system symptom. The plasma therapy combined corticosteroids with antiplatelet drugs was applied in all patients. 4 patients survived and 2 patients died. Conclusion.. TTP is not completely have pentad. Early application of plasma exchange combined corticosteroids is effective for most TTP patients.

关 键 词：血栓性血小板减少性紫癜 早期诊断 血浆置换 

分 类 号：R554.6[医药卫生—血液循环系统疾病]