高效液相色谱串联质谱法分析烟草中15种农药残留  

Determination of Fifteen Pesticide Residues in Tobacco with LC-MS/MS

作　　者：严会会[1] 胡斌[2] 刘惠民[2] 马海鸣[1] 王丽杰[1] 石杰[1] 

机构地区：[1]郑州大学化学系 [2]中国烟草总公司郑州烟草研究院

出　　处：《烟草科技》2011年第7期43-47,共5页Tobacco Science & Technology

基　　金：国家自然科学基金资助项目"药物食品的光谱及色谱分析研究"(No.J0830412)

摘　　要：为检测烟草中的"吡蚜酮"等农药残留,建立了乙腈提取、分散固相萃取净化和高效液相色谱-质谱联用(LC-MS/MS)快速分析烟草中15种农药残留的方法。结果表明:15种农药在0.10,0.25和0.50μg/g 3个加标水平的回收率为70.43%～117.81%,相对标准偏差(RSD)为1.16%～13.89%,检出限为0.004～0.030μg/g。该方法适合于批量烟草样品中多种农药残留的快速分析。A method for rapidly determining fifteen pesticides, such as pymetrozine and others, in tobacco with LC-MS/MS was developed. Samples were extracted by acetonitrile, cleaned up by dispersive solid-phase extraction and finally detected with LC-MS/MS. The results showed that the recoveries of the fifteen pesticides ranged from 70.43% to 117.81% at the standard＇s levels of 0.1,0.25 and 0.5-μg,the relative standard deviation （RSD） ranged from 1.16% to 13.89% ,and the limit of detection was from 0.004 to 0.030 μg/g. This method was suitable for the rapid analysis of multiple pesticide residues in batches of tobacco samples.

关 键 词：LC—MS/MS 烟草 农药残留 QUECHERS 

分 类 号：S481.8[农业科学—农药学]