肠型脂肪酸结合蛋白在成人危重症胃肠功能衰竭早期诊断中的价值  

The early diagnosis value of intestinal fatty acid binding protein in gastrointestinal failure adults

作　　者：柳刚[1] 江传燊[1] 李海涛[1] 

机构地区：[1]南京军区福州总医院消化内科,福建福州350025

出　　处：《中国医药导报》2011年第22期158-159,共2页China Medical Herald

摘　　要：目的:分析肠型脂肪酸结合蛋白(intestinal fatty acid binding protein,Ⅰ-FABP)与危重症胃肠功能衰竭的关系。方法:将我院消化内科重症监护室病房2009年3月～2010年3月住院的37例胃肠道疾病患者分为衰竭组(21例)和非衰竭组(16例),另选与前两组相匹配的同期在我院门诊行健康体检的正常成人37例作为对照组,用酶联免疫吸附法(ELISA)分别检测三组患者血清I-FABP浓度。结果:三组患者血清Ⅰ-FABP浓度分别为(11.19±1.92)、(6.13±2.14)、(3.48±2.31)μg/L,三组血清浓度的比较,差异具有高度统计学意义(P<0.01)。结论:血清Ⅰ-FABP在成人危重症胃肠功能衰竭早期即出现增高,可作为成人危重症胃肠功能衰竭早期诊断的一个敏感指标。Objective： To analyze the relationship between the I-FABP level and critical gastrointestinal failure. Methods： 37 patients in the digestive system ICU department were divided into the gastrointestinal failure group （n=21）, non-gas- trointestinal failure group （n=16） from March 2009 to March 2010, with 37 health adults in the same time as the control group. Then the I-FABP levels were measured in three groups by ELISA. Results： The I-FABP in three groups were （11.19±1.92）, （6.13±2.14）, （3.48±2.31） μg/L, respectively. There were significant differences between three groups in the I- FABP level （P〈0.01）. Conclusion： The I-FABP levels in patients with gastrointestinal failure have increased in early peri- od, it can be used as a sensitive index in the early gastrointestinal failure.

关 键 词：肠型脂肪酸结合蛋白 胃肠功能衰竭 酶联免疫吸附法 

分 类 号：R725.7[医药卫生—儿科]