低分子肝素治疗进展型脑梗死22例  

Low Molecular Heparin for Treating Acute Progressing Cerebral Infarction in 22 Cases

作　　者：朱亚兰[1] 

机构地区：[1]四川省广汉市人民医院神经内科,四川广汉618300

出　　处：《中国药业》2011年第15期67-68,共2页China Pharmaceuticals

摘　　要：目的探讨低分子肝素治疗进展型脑梗死的临床疗效。方法选取2008年3月至2010年8月进展型脑梗死患者47例,随机分为两组,治疗组22例给予低分子肝素5000 U,每12 h皮下注射1次,连用7 d,并口服拜阿司匹林100 mg,每天1次。对照组25例给予拜阿司匹林口服100 mg,每天1次。观察神经功能缺失症状是否改善和治疗后神经功能缺损评分,评价临床疗效。结果神经功能缺失症状的改善,治疗组明显优于对照组(P<0.01)。结论低分子肝素能有效阻止进展型脑梗死病情进展,改善神经功能缺损,且副作用小。Objective To investigate the curative effect of low molecular heparin in the treatment of acute progressing cerebral infarction.Methods Forty-seven cases of acute progressing cerebral infarction in our hospital from March,2008 to August,2010 were selected and randomly divided into two groups.Tweenty-two cases in the treatment group were treated by subcutaneous injection of 5 000 un its low molecular heparin once every 12 h and oral aspirin 100 mg once daily for successive 7 d.Those in the control group were treated by oral aspirin 100 mg o nce daily alone.The curative effect was evaluated by observing the improvement o f patients′neurological deficit symptoms and the score of neurological deficit. Results The stop and improvement of patients′neurological deficit symptoms in t he treatment group were significantly better than those in the control group（P〈0.01）.Conclusion Low molecular heparin can stop the disease progression and im prove the neurological deficits effectively with less adverse reactions.

关 键 词：低分子肝素 进展型脑梗塞 疗效 

分 类 号：R969.4[医药卫生—药理学] R973.2[医药卫生—药学]