胰岛素联合生长因子及湿性敷料处理难愈性烧伤残余创面的疗效研究  

Insulin,growth factor and moist dressing for treatment of refractory residual burn wound

作　　者：方梅[1] 柳晖[1] 黄丽容[1] 陈武鹏[1] 袁志敏[1] 向红霞[1] 吴继红[1] 刘胜[1] 

机构地区：[1]深圳市宝安区人民医院ICU,广东深圳518101

出　　处：《护理学杂志》2011年第14期1-3,共3页

基　　金：广东省深圳市科技局2010年科技基金资助项目(201002147)

摘　　要：目的研究胰岛素联合生长因子及湿性敷料处理难愈性小面积深度烧伤残余创面的临床疗效。方法将40例深度烧伤后形成小面积难愈性残余创面168处的患者进行自身对照,在早期少量多次清创的基础上,采用胰岛素联合生长因子贝复剂湿敷后给予湿性敷料包扎(改进法,100处),与仅外喷生长因子后给予碘伏敷料湿敷包扎的常规法(68处)进行效果比较。结果两法换药疼痛评分、创面平均愈合时间、创面愈合率、不同时期创面分泌物细菌培养阳性率比较,差异有统计学意义(均P<0.01)。结论采用胰岛素联合生长因子及湿性敷料处理难愈性小面积深度烧伤残余创面,能提高创面愈合速度及愈合质量,减少患者痛苦,缩短住院时间。Objective To reveal therapeutic effect of insulin,growth factor and moist dressing used together for treatment of refractory residual wound induced by deep burn injury.Methods Forty patients with 168 refractory residual wounds induced by deep burn injury were enrolled in the study.By using self-controlled method,on the basis of early debridement,68 wounds were sprayed with growth factor（bFGF） and bandaged with iodophor dressing（the conventional method）,and 100 were compressed with insulin and growth factor（bFGF）,and bandaged with moist dressing of Urgotul SSD dressing（the improved method）.Results Compared with the conventional method,pain score during dressing change,wound healing time,wound healing rate,and positive bacterial cultures of wound secretions in different periods had significant differences by using the improved method（P0.01 for all）.Conclusion Using insulin,growth factor and moist dressing together for treatment of refractory residual wound induced by deep burn injury can significantly shorten wound healing time,promote healing quality,allievate patients′ pain,and shorten length of hospital stay.

关 键 词：烧伤 难愈性残余创面 胰岛素 生长因子 优拓敷料 碘伏 换药 创面处理 

分 类 号：R472.9[医药卫生—护理学]