合成N-乙基哌嗪的催化剂改性研究  

Modification of the catalysts for synthesis of N-ethylpiperazine

作　　者：兰婷[1] 李穆琼[1] 张俊娜[1] 苏海鹏[2] 

机构地区：[1]第四军医大学药学系,陕西西安710032 [2]西安近代化学研究所,陕西西安710065

出　　处：《应用化工》2011年第7期1205-1208,共4页Applied Chemical Industry

摘　　要：采用离子交换法对合成N-乙基哌嗪的催化剂γ-氧化铝进行改性,考察了催化剂制备方法对反应的影响。结果表明,γ-Al2O3在室温下经1.00 mol/L的Cu(NO3)2溶液浸渍48 h,110℃干燥3 h,500℃焙烧6 h,于0.6 MPa压力的反应器内、300℃,氢气还原3 h后具有较好的活性和选择性,可提高N-乙基哌嗪收率和哌嗪转化率。The modification of catalysts for the synthesis of N-ethylpiperazine by ion exchange was investigated.The effect of synthetic method of catalyst on reaction were discussed.Results showed that γ-alumina infused for 48 h at room temperature in 1.00 mo1/L Cu（NO3）2 solution,dried for 3 h at 110 ℃,baked for 6 h at 500 ℃,reduction for 3 h at 300 ℃ under hydrogen pressure of 0.6 MPa in reactor,the γ-alumina catalyst had better activity and selectivity.The conversion of N-ethylpiperazine and the yield of piperazine both increased.

关 键 词：N-乙基哌嗪 Γ-氧化铝 离子交换法 

分 类 号：TQ463.5[化学工程—制药化工]