高渗氯化钠复合琥珀酰明胶治疗失血性休克的临床观察  

The clinical observation of hypertonic sodium chloride compound succinylated gelatin in curing hemorrhagic shock

作　　者：龙雄[1] 郑天勇[1] 郭宇峰[1] 何炳泉[1] 吴靖波[1] 

机构地区：[1]南方医科大学附属小榄医院,广东中山528415

出　　处：《中国当代医药》2011年第21期98-99,共2页China Modern Medicine

摘　　要：目的:观察高渗氯化钠复合琥珀酰明胶治疗失血性休克的临床效果。方法:选择本院住院的失血性休克患者60例,将其随机分为高渗氯化钠液组(HSC组)(n=30)和高渗氯化钠复合琥珀酰明胶组(HSCG组)(n=30),观察患者休克复苏的效果,并记录患者复苏前后血流动力学的变化。结果:两组治疗前后比较休克症状均有改善,MAP、CVP、PCWP上升,尿量增加,血乳酸下降;HSCG组经治疗后MAP、CVP、PCWP上升幅度及尿量明显高于HSC组(P<0.01),且作用维持时间长,血乳酸下降更加明显。结论:高渗氯化钠复合琥珀酰明胶在复苏急性失血性休克的患者中效果优于高渗氯化钠。Objective：To observe the clinical effects of the treatment of hypertonic sodium chloride compound succinylated gelatin in hemorrhagic shock.Methods：60 cases of hemorrhagic shock patients who were picked up by emergency department were randomly divided into hypertonic sodium chloride（HSC） group（n=30） and hypertonic sodium chloride compound succinylated gelatin（HSCG） group（n=30）.Observed the effects of resuscitation and recorded the hemodynamic changes before and after the treatment for the patients.Results：Shock symptoms in both groups were relieved.MAP,CVP,PCWP and urine were increased while lactate was decreased.These changes in the HSCG group were more significant.Conclusion：The hypertonic saline solution associating with gelofusion has better effect in the recovery for the hemorrhagic shock patients than hypertonic sodium chloride solution.

关 键 词：失血性休克 复苏 高渗氯化钠 琥珀酰明胶 

分 类 号：R459.7[医药卫生—急诊医学]