糖化血红蛋白在诊断妊娠期糖尿病中的作用及意义  

The function and significance of glycosylated hemoglobin in diagnosis of gestational diabetesmellitus

作　　者：蓝燕[1] 李丽芳[1] 

机构地区：[1]广西壮族自治区河池市人民医院妇产科,广西河池547000

出　　处：《中国当代医药》2011年第21期115-116,共2页China Modern Medicine

摘　　要：目的:探讨糖化血红蛋白(HbA1c)在诊断妊娠期糖尿病(GDM)中的作用及意义。方法:2010年2月～2011年2月,分别检测68例GDM孕妇和100例正常孕妇HbA1c、口服糖负荷实验(OGCT)和空腹血糖(FPG)水平。结果:GDM组FPG、OGCT、HbA1c水平均明显高于对照组(P<0.05)。GDM组FPG、OGCT、HbA1c的阳性率均明显高于对照组(P<0.05),其中以HbA1c的阳性率最高,为85.3%。HbA1c>6.0%的GDM孕妇羊水过多、胎膜早破和新生儿窒息发生率明显高于HbA1c≤6.0%的孕妇(P<0.05)。结论:HbA1c水平在GDM患者中明显升高,诊断GDM具有较高的阳性率,对HbA1c水平的监测有利于降低母婴并发症发生率,为糖尿病的血糖水平监测提供了新的方法。Objective：To discuss the function and significance of HbA1c in diagnosis of gestational diabetesmellitus（GDM）.Methods：68 cases of GDM patients and 100 cases of normal pregnant women were detected with HbA1c,OGCT and FPG.Results：The levels of HbA1c,OGCT and FPG in GDM group were significantly higher than those in control group（P〈0.05）.The positive rates of HbA1c,OGCT and FPG in GDM group were significantly higher than those in control group（P〈0.05）.The incidences of maternal polyhydramnios,premature rupture of membranes and neonatal asphyxia in HbA1c〉6.0% group were significantly higher than those in HbA1c≤6.0% group（P〈0.05）.Conclusion：The levels of HbA1c were significantly increased in GDM patients and have higher positive rates,which is good for lowing incidence of maternal complications and can provide a new method for monitoring Diabetes blood glucose.

关 键 词：糖化血红蛋白 妊娠期糖尿病 诊断 空腹血糖 

分 类 号：R446.1[医药卫生—诊断学]