冠心病心力衰竭中医证候与心功能分级及超声心动相关指标的研究  

TCM syndromes of CHD-related heart failure,cardiac function grading and ultrasonic cardiogram indexes

作　　者：陈婵[1] 张鹏[1] 王娟[1] 赵慧辉[2] 孟永梅[1] 王伟 

机构地区：[1]北京中医药大学基础医学院,北京100029 [2]北京中医药大学研究生院

出　　处：《北京中医药大学学报》2011年第7期491-494,共4页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家中医药管理局行业专项资助项目(No.200807007)

摘　　要：目的探讨冠心病心力衰竭中医证候与心功能分级及超声心动相关指标的关系。方法在文献调研和专家咨询的基础上制定临床四诊信息采集表,对98例冠心病心力衰竭患者行超声心动检测,同时采集患者的四诊信息,判断其心功能级数和中医证候分型,将数据结果进行统计分析。结果气虚血瘀组、气虚血瘀兼痰浊组主要分布于心功能Ⅱ级,气虚血瘀兼水停、气虚血瘀兼痰水互结组主要分布于心功能Ⅲ级;气虚血瘀兼水停、气虚血瘀兼痰水互结组左房扩大出现率较高,与其他两证相比具有显著差异(P<0.05),气虚血瘀兼痰水互结组左室收缩功能不全出现率较高,与气虚血瘀组相比有显著差异(P<0.01)。左房扩大在心功能Ⅲ级组出现率较高,与心功能Ⅱ级组相比有显著差异(P<0.05);心功能Ⅱ级组左室舒张功能不全出现率显著高于心功能Ⅳ级组(P<0.05),心功能Ⅲ、Ⅳ级组左室收缩功能不全出现率均显著高于心功能Ⅱ级组(P<0.01)。结论中医证候与心功能分级及超声心动指标密切相关,随着心功能的变化,中医证候的分布具有一定特点。Objective To investigate the relationship among TCM syndromes, cardiac function grading and ultrasonic cardiogram indexes of coronary heart disease （CHD）-related heart failure. Methods The table for collecting clinical information of TCM four examinations was made based on the literature survey and experts consultation. The patients （n = 98 ） with CHD-related heart failure were examined with ultrasonic cardiogram for estimating their cardiac function grades and TCM syndrome types, and their information of four examinations were collected at the same time. All data were analyzed statistically. , Results The group of qi-deficiency blood-stasis, and group of qi-deficiency blood-stasis combining phlegm-turbidity distributed mainly in group II cardiac function. The type of qi-deficiency blood-stasis combining water-retention and group of qi-deficiency blood-stasis combining phlegm-water intermingling distributed mainly in grade 1II cardiac function. The occurrence rate of left atrial enlargement was higher in the group of qi-deficiency blood-stasis combining water-reter-retention and group of qi-deficiency blood-stasis combiming phlegm-water intermingling compared with other two syndrome groups （P 〈 0. 05）, The occurrence rate of left ventricle systolic dysfunction was higher in blood-stasis combining phlegm-water intermingling compared with the group of the group of qi-deficiency qi-deficiency blood-stasis （P 〈0. 01 ）. The occurrence rate of left atrial enlargement was higher in the group of grade III cardiac function compared with group of grade II cardiac function （ P 〈 0.05 ）. The occurrence rate of left ventricle diastolic dysfunction was higher significantly in the group of grade II cardiac function than that in the group of grade IV cardiac function （P 〈 0. 05 ）. The occurrence rate of left ventricle systolic dysfunction was higher significantly in the group of grade III cardiac function and grade IV cardiac function than that in the group of grade II cardiac function �

关 键 词：冠心病心力衰竭 中医证候 心功能分级 超声心动 

分 类 号：R541.4[医药卫生—心血管疾病]