补肾调周法联合克罗米芬用于不孕症的临床研究  

Clinical observation on the effects of TKRPM combined with clomiphene for infertility

作　　者：许佳[1] 

机构地区：[1]东南大学医学院附属江阴医院妇科,214400

出　　处：《国际中医中药杂志》2011年第8期676-680,共5页International Journal of Traditional Chinese Medicine

摘　　要：目的观察补肾调周疗法联合克罗米芬治疗不孕症的临床疗效。方法采用随机数字表法将患者随机分为两组各30例，中药组采用补肾调周法治疗，中西药组在中药组治疗基础上联合克罗米芬促排卵治疗，两组均治疗3个月为1个疗程，选择临床中医肾虚症状积分、基础体温、B超结果、血清激素水平为观察指标。结果中药组总有效率为93．3％，妊娠率为33.3％，平均治愈时间为（8．20±2．35）个月；中西药组总有效率为100％，妊娠率为20％，平均治愈时间为（5．17±1．72）个月。两组总有效率（u=0．358）及妊娠率（X^2=1．346）比较，差异无统计学意义（P均〉0．05），但两组小孕症患者的平均治愈时间比较，差异有统计学意义（P〈0．05）。结论中西药联合治疗不孕症，以克罗米芬改善内分泌环境，中药补肾气、调冲任，两者结合标本同治、取长补短，可明显缩短治疗时间。Objective To summary Jiangsu Province Hospital of TCM Professor XiaGuiCheng＇s experience on treatment of infertility by the method of Tonifying the Kidney and Regulating the Period of Menses （TKRPM）, meanwhile to observe the clinic curative effect of TKRPM combined with clomiphene for infertility. Methods The patients were randomly recruited into a TCM group and a TCM combined western medicine group by digital randomized methed, 30 cases in each group. The TCM treated group was treated by the method of TKRPM, while the other group was treated by TCM combined with clomiphene. Both groups were treated for three months. Syndromes, basal body temperature, results of B ultrasonic, and hormone in serum were observed. Results In TCM treated group, the clinic effective rate was 93.3%, the pregnant ratio was 33.3%, mean-cure-time for pregnant was （8.20±2.35）months; while in TCM combined western medicine group, the clinic effective rate was 100%, the pregnant ratio was 20%, and mean-cure-time for pregnant was （ 5.17 ± 1.72 ） months .The clinic effective rates （ U= 0.358 ） and the pregnant ratios （x^2 = 1.346 ） of two groups were not markedly difference （P〉0.05）, but the mean-cure-time for pregnant of the two groups was markedly difference（P〈0.05）. Conclusion TKRPM combined with induction drugs can cure infertility in a shorter time than using TCM only. Western medicine improves endocrine environment, while traditional Chinese medicine regulates the relationship among kidney, TianGui and the uterus fundamentally. The method will be more acceptable to patients.

关 键 词：排卵障碍性不孕症 监测排卵 诱导排卵 肾虚 补肾调周法 

分 类 号：R711.6[医药卫生—妇产科学]