丰台区已婚妇女宫颈病变与HPV感染的分析  

Correlation analysis of cervical intraepithelial neoplasia and HR-HPV infection in married women in Fengtai District

作　　者：唐艳[1] 张静[1] 房春玉 史坤翀[1] 

机构地区：[1]北京市丰台区妇幼保健院,北京100067

出　　处：《中国妇幼健康研究》2011年第4期418-419,422,共3页Chinese Journal of Woman and Child Health Research

摘　　要：目的探讨北京市丰台区已婚妇女宫颈病变与HR-HPV感染的现患状况及其相关性。方法采用横断面调查方法，对北京市丰台区882名已婚妇女进行问卷调查、妇科检查、宫颈液基细胞学检测。结果①882例调查对象平均年龄45．2±8．0岁，宫颈病变发病高峰年龄为30～34岁（12．16％）；②宫颈病变患者53例，患病率为6．01％；③HR．HPV感染率10．77％，HR-HPV感染阳性人群中CIN的患病率为31．6％，明显高于HR-HPV阴性人群中CIN的患病率2．9％；④宫颈病变的相关因素还包括孕次。结论30-34岁为北京市丰台区已婚妇女宫颈病变的高发年龄组；HR-HPV感染是宫颈病变的高危因素；针对宫颈病变的相关危险因素采取积极的健康宣教和有效的预防措施，降低富颈癌的发病率。Objective To investigate the sickness status and correlation between cervical intraepithelial neoplasia （CIN） and HR-HPV infection in married women in Fengtai District, Beijing. Methods Based on cross-sectional survey, 882 married women were investigated with unified questionnaires, gynecological examination and cervical liquid-based cytology test. Results The average age of 882 subjects was 45.2 ± 8.0 years, and the peak age of onset of CIN was 30 to 34 years old （ 12.16% ）. There were 53 cases of CIN and the prevalence rate was 6.01%. The infection rate of high-risk human papilloma virus（HR-HPV） was 10.77%. Among the HR-HPV positive cytological subjects, the prevalence rate of CIN was 31.6%, which was significantly higher than that （2.9%） in negative cytological subjects. The influencing factor of CIN also included gravidity. Conclusion In Fengtai, married women between 30-and 34-year old are the subjects who have high risk of onset of CIN, and HR-HPV infection is the high-risk factor of CIN. Positive health education and effective preventions should be carried out to decrease the incidence of CIN.

关 键 词：宫颈病变 高危型人乳头瘤病毒 相关分析 已婚妇女 

分 类 号：R173[医药卫生—妇幼卫生保健] R711[医药卫生—公共卫生与预防医学]